End-stage endometrial cancer?
Last year, my mother was diagnosed with stage IV endometrial cancer.
The doctor mentioned that although the tumor was surgically removed, there are still some cancer cells near the rectal mucosa, and surgery in that area is challenging.
She has completed chemotherapy and radiation therapy earlier this year, and both X-ray and MRI scans have shown normal results.
I would like to ask if these two tests can indicate whether the cancer cells have metastasized.
Additionally, why is intestinal adhesion considered a sign of advanced stage cancer? What discomfort can occur with intestinal adhesion? Thank you, doctor!
TT, 30~39 year old female. Ask Date: 2010/06/10
Dr. Cai Yonglong reply Obstetrics and Gynecology
Dear Dr.
Tsai Yong-long of the Department of Obstetrics and Gynecology at Tainan Hospital, Ministry of Health and Welfare:
1.
It is necessary to perform a blood test for carcinoembryonic antigen (CEA) and a biopsy via colonoscopy to confirm the diagnosis.
2.
Metastasis to the rectum is classified as distant metastasis, thus it can be determined as terminal stage.
3.
Intestinal adhesions can affect gastrointestinal motility, often leading to cramping or diarrhea after overeating or eating too quickly.
Please visit the outpatient clinic, where the physician will provide a detailed explanation.
Wishing you good health and all the best!
Reply Date: 2010/06/10
More Info
Understanding endometrial cancer, particularly in late stages, involves a comprehensive look at the disease's progression, treatment options, and the implications of diagnostic tests.
Endometrial cancer, or cancer of the lining of the uterus, can vary significantly in its behavior and prognosis based on its stage at diagnosis. When a patient is diagnosed with late-stage endometrial cancer, it typically means that the cancer has spread beyond the uterus to nearby structures, such as the rectum, or even to distant organs. The presence of cancer cells near the rectal mucosa, as mentioned in your mother's case, indicates a more advanced disease, which can complicate treatment options.
In terms of diagnostic imaging, X-rays and MRI (Magnetic Resonance Imaging) are valuable tools for assessing the extent of cancer spread. An MRI, in particular, is highly effective for visualizing soft tissues and can provide detailed images of the uterus, rectum, and surrounding structures. However, while these imaging techniques can indicate the presence of tumors or abnormalities, they may not always definitively confirm the presence of cancer cells. For example, they can show masses or changes in tissue but may not distinguish between benign and malignant processes without a biopsy. Therefore, while normal results from these tests are encouraging, they do not guarantee that there are no remaining cancer cells or that the cancer has not metastasized.
Regarding the term "intestinal adhesion" (or "adhesions"), it refers to bands of scar tissue that can form between abdominal tissues and organs, often as a result of previous surgeries or inflammation. In the context of cancer, adhesions can complicate surgical interventions and may indicate that the cancer has invaded surrounding tissues. The presence of adhesions alone does not automatically classify the cancer as "late-stage," but it can be a sign of advanced disease due to the associated complications. Symptoms of intestinal adhesions can include abdominal pain, bloating, and changes in bowel habits, which may lead to discomfort or obstruction.
The treatment for late-stage endometrial cancer often involves a combination of surgery, chemotherapy, and radiation therapy, as you've noted your mother has undergone. The goal of these treatments is to eliminate as much of the cancer as possible and to manage symptoms. Chemotherapy and radiation can help reduce the size of tumors and kill remaining cancer cells, but they also come with side effects that can impact quality of life.
It's essential to maintain open communication with your mother's healthcare team. They can provide insights into the specific findings from imaging studies and what they mean for her prognosis and treatment plan. Additionally, they can help manage any symptoms related to adhesions or other complications, ensuring that your mother receives comprehensive care tailored to her needs.
In summary, while imaging studies like X-rays and MRIs are crucial in assessing cancer spread, they are not definitive for ruling out cancer. The presence of adhesions can indicate advanced disease but does not solely determine the stage. Ongoing treatment and monitoring are vital in managing late-stage endometrial cancer, and understanding the nuances of these diagnostic tools can help in navigating the complexities of care.
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