Co-administration
Hello Dr.
Huang,
Post-meal consumption: Eye protection (bilberry extract) + fish oil + taurine.
Post-meal consumption: Vitamin C + E + lecithin.
Q1: It is said that fish oil is prone to oxidation, so it needs to be paired with Vitamin E, but Vitamin E also requires Vitamin C for redox assistance.
How should these be combined for consumption?
Q2: It is said that excessive Vitamin E can cause vascular bleeding.
Q3: If taking Vitamin E at 400 I.U., is it safe to take one capsule daily?
Q4: If there is mild anemia but B12 and folate levels are elevated in immune testing, how should this be addressed? (Assuming no meat consumption)
Red Blood Cell (RBC) count: 3.5
Hemoglobin: 12.1
Hematocrit: 34.7
Mean Corpuscular Volume (MCV): 99
Mean Corpuscular Hemoglobin (MCH): 34.5
Mean Corpuscular Hemoglobin Concentration (MCHC): 34.8
Platelet Count: 269
Red Cell Distribution Width (RDW): 12.9
Folate immune analysis: >23
Vitamin B12 immune analysis: 1121
Please clarify these concerns.
Thank you.
Varina, 30~39 year old female. Ask Date: 2010/11/13
Dr. Huang Shenggang reply Pharmacology
Hello Varina: Regarding your question, I am curious why you are taking so many dietary supplements.
If fish oil is prone to oxidation and needs to be paired with Vitamin E, which in turn requires Vitamin C for redox assistance, how should they be combined? In fact, you don't need to worry too much; you can consult the pharmacist or nutritionist where you purchased the products.
Any vitamin has a limited intake for the human body, and excessive amounts are not beneficial.
Avoid purchasing dietary supplements from unknown sources.
If you need to combine supplements, please consult the place of purchase first, as this will help you maintain a strong and healthy body.
Reply Date: 2010/11/13
More Info
When considering optimal supplement combinations for eye health and anemia management, it's essential to understand the roles of each supplement and how they interact with one another. Let's address your questions systematically.
Q1: Fish Oil and Vitamin E Interaction
Fish oil is rich in omega-3 fatty acids, which are beneficial for eye health, particularly in reducing inflammation and supporting retinal function. However, as you mentioned, fish oil can oxidize, which is why it's often recommended to take it with antioxidants like Vitamin E. Vitamin E helps protect the omega-3 fatty acids from oxidation, thus preserving their efficacy.
Vitamin C is another antioxidant that can regenerate Vitamin E after it has neutralized free radicals. Therefore, a good strategy would be to take fish oil with Vitamin E and Vitamin C, ensuring that you are consuming them at the same time or within a close timeframe. This combination can help maximize the benefits of each supplement while minimizing the risk of oxidation.
Q2: Risks of Vitamin E Overdose
Vitamin E is a fat-soluble vitamin, meaning it can accumulate in the body. While it is essential for various bodily functions, excessive intake can lead to adverse effects, including an increased risk of bleeding. This is particularly concerning for individuals on anticoagulant medications or those with bleeding disorders. The tolerable upper intake level for adults is set at 1,000 mg (or 1,500 IU) per day. Therefore, it's crucial to monitor your intake and consult with a healthcare provider if you are considering high doses.
Q3: Daily Intake of 400 IU of Vitamin E
Taking 400 IU of Vitamin E daily is generally considered safe for most individuals, especially if it is part of a balanced diet. However, it is essential to ensure that this amount does not exceed the recommended dietary allowance (RDA) for your specific health needs. If you are not experiencing any adverse effects and your healthcare provider has approved this dosage, it should be fine. Always consider discussing any supplementation with your doctor, particularly if you have underlying health conditions.
Q4: Managing Mild Anemia with High B12 and Folate Levels
In your case, where you have mild anemia but elevated levels of Vitamin B12 and folate, it is crucial to identify the underlying cause of the anemia. Elevated B12 levels can sometimes indicate liver disease or other metabolic issues rather than a deficiency. Since you mentioned that you do not consume meat, it’s essential to ensure you are getting adequate iron from plant-based sources. Foods rich in iron include lentils, beans, tofu, quinoa, and fortified cereals.
Additionally, Vitamin C can enhance iron absorption, so pairing iron-rich foods with Vitamin C sources (like citrus fruits, bell peppers, or broccoli) can be beneficial. If your anemia persists despite dietary adjustments, it may be worthwhile to consult a healthcare provider for further evaluation and potential supplementation with iron or other necessary nutrients.
Conclusion
In summary, when managing eye health and anemia, a well-rounded approach that includes appropriate supplementation, dietary adjustments, and regular monitoring is essential. The combination of fish oil, Vitamin E, and Vitamin C can support eye health, while addressing anemia may require a focus on iron-rich foods and understanding the implications of elevated B12 and folate levels. Always consult with a healthcare professional before making significant changes to your supplement regimen or diet, especially in the context of existing health conditions.
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