CIS: Is It the Same as Stage 0 Cervical Cancer? - Obstetrics and Gynecology

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Carcinoma in situ (CIS)


Hello, is CIS the term for stage 0 cervical cancer? Is a cervical conization performed to assess the spread of cancer cells? My mother has been feeling quite down and depressed lately, and I can't discuss this in detail with the doctor in front of her.
I kindly ask for your clarification! Thank you!

karen, 30~39 year old female. Ask Date: 2011/03/08

Dr. Lü Lizheng reply Obstetrics and Gynecology


Dear Karen,
CIS stands for Carcinoma in situ, also known as localized cancer, which means it has not metastasized and has not invaded deeper tissues.
Therefore, it is relatively safer and is considered stage 0.
As long as the cervical cone biopsy successfully removes all abnormal cells, it can be considered cured.
The recurrence rate is very low, approximately only 1%, and 99% of individuals will have no further issues.
Please remember to review the pathological report from the surgery to confirm that all abnormal cells have been completely excised.
After that, follow-up should be done every three months to monitor for any potential recurrence.
In the unlikely event of a recurrence, further excision can be performed.
Please do not worry too much.
Wishing you peace and health.
Sincerely,
Dr.
Li-Cheng Lu
Director, Department of Obstetrics and Gynecology
Taoyuan General Hospital, Ministry of Health and Welfare

Reply Date: 2011/03/08

More Info


Cervical Intraepithelial Neoplasia (CIN) and Carcinoma In Situ (CIS) are terms that often come up in discussions about cervical cancer, particularly when it comes to early detection and treatment. To answer your question directly: yes, CIS is indeed considered Stage 0 cervical cancer. This means that the cancerous cells are present in the cervix but have not invaded deeper tissues or spread to other parts of the body. In this stage, the cancer is localized, and if treated appropriately, the prognosis is generally very good.

When it comes to the treatment of CIS, one common procedure is a cone biopsy, also known as a conization or cervical conization. This surgical procedure involves removing a cone-shaped section of the cervix that contains the abnormal cells. The primary goal of this procedure is to ensure that all abnormal cells are removed, which can effectively treat the cancer at this early stage.
Regarding your concern about whether the extent of cancer cell spread needs to be considered during a cone biopsy: in the case of CIS, the cancer is still confined to the surface layer of the cervix, and there is no invasion into deeper tissues. Therefore, the focus during the cone biopsy is primarily on ensuring that all abnormal cells are excised. However, the pathology report following the procedure is crucial. It will provide information on whether the margins of the excised tissue are clear of cancerous cells, which indicates that the abnormal cells have been completely removed. If the margins are not clear, further treatment may be necessary.

It's understandable that your mother is feeling anxious and depressed about her diagnosis. The emotional toll of a cancer diagnosis, even at an early stage like CIS, can be significant. It’s important to provide her with support and reassurance. The likelihood of recurrence after a successful cone biopsy for CIS is relatively low, around 1% to 10%, depending on various factors, including the completeness of the excision and follow-up care. Regular follow-ups, typically every three months initially, are recommended to monitor for any signs of recurrence.

In terms of the emotional aspect, it might be beneficial for your mother to speak with a mental health professional or a support group for individuals facing similar health challenges. This can help her process her feelings and provide her with coping strategies.

In summary, CIS is indeed Stage 0 cervical cancer, and the focus during treatment is on ensuring complete removal of the abnormal cells. The prognosis is generally favorable, especially with appropriate follow-up care. Encourage your mother to stay positive and to engage in open discussions with her healthcare team about her concerns and treatment options. Regular monitoring and support can significantly improve her emotional well-being during this challenging time.

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