7-valent and 13-valent pneumococcal vaccines?
Hello Dr.
Hsiao, I apologize for bothering you again.
My question is as follows: On April 22, 2011, I took my child to the well-child clinic (at one year old) and received the varicella, measles, and the fourth dose of the 7-valent pneumococcal vaccine.
The nurse informed me that the 13-valent pneumococcal vaccine is now available.
Could you please let me know how long I should wait before my child can receive one dose of the 13-valent pneumococcal vaccine (including serotype 19A)? Thank you for taking the time to respond, Dr.
Hsiao.
Thank you, Jack Li, April 29, 2011.
Jack, 30~39 year old female. Ask Date: 2011/04/29
Dr. Xiao Kaiwen reply Pediatrics
There should be an interval of at least one month after the last dose of the 7-valent pneumococcal vaccine.
In the United States, it is recommended that there be an interval of at least eight weeks between PCV7 and PCV13.
Reply Date: 2011/04/29
More Info
The 7-valent pneumococcal vaccine (PCV7) and the 13-valent pneumococcal vaccine (PCV13) are both designed to protect against infections caused by Streptococcus pneumoniae, a bacterium that can lead to serious illnesses such as pneumonia, meningitis, and otitis media (ear infections). Understanding the differences between these two vaccines is crucial for making informed decisions about immunization for children.
Differences Between PCV7 and PCV13:
1. Serotype Coverage: The most significant difference between PCV7 and PCV13 is the number of pneumococcal serotypes they cover. PCV7 protects against seven serotypes of the bacterium, while PCV13 covers an additional six serotypes, bringing the total to thirteen. The additional serotypes in PCV13 include 1, 3, 5, 6A, 7F, and 19A, which are associated with more severe disease and have become more prevalent in recent years.
2. Efficacy: Studies have shown that PCV13 provides broader protection against pneumococcal disease compared to PCV7. This is particularly important as the epidemiology of pneumococcal infections evolves, with non-vaccine serotypes becoming more common. By vaccinating with PCV13, children are better protected against these emerging strains.
3. Recommendations: The Centers for Disease Control and Prevention (CDC) recommends that children receive PCV13 as part of their routine immunizations. For children who have already received doses of PCV7, it is advised to administer PCV13 to ensure they are protected against the additional serotypes.
Timing for Vaccination:
In your specific case, since your child received the fourth dose of PCV7 on April 22, 2011, the recommendation is to wait at least one month before administering the PCV13 vaccine. In the U.S., the CDC suggests that there should be an interval of at least eight weeks between the last dose of PCV7 and the first dose of PCV13. This is to ensure that the immune system has adequately responded to the previous vaccine before introducing another.
Importance of Vaccination:
Vaccination against pneumococcal disease is particularly important for young children, as they are at a higher risk for severe infections. Pneumococcal disease can lead to hospitalization and, in some cases, long-term complications. By ensuring that your child receives the appropriate vaccinations, you are helping to protect them from these serious health risks.
Conclusion:
In summary, the transition from PCV7 to PCV13 is a critical step in enhancing the protection of children against pneumococcal disease. If your child has received PCV7, it is essential to follow up with PCV13 after the recommended interval. Always consult with your healthcare provider to ensure that your child’s vaccination schedule is up to date and to address any specific concerns you may have regarding their health and immunization needs.
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