Cold with wheezing and chest discomfort?
Hello, doctor.
I have been taking corticosteroids and immunosuppressants for a long time due to an autoimmune disease.
Since I started these medications, every time I catch a cold (which I can feel more distinctly), I experience noticeably increased breathing rate, chest discomfort, and wheezing.
I have tried several cold medications, but they haven't been very effective.
The most effective way to alleviate my discomfort is by using a bronchodilator inhaler, which quickly and effectively improves my condition, even calming my heart rate that accelerates due to wheezing and chest discomfort.
My IgE level is 200, and ECP is 50, but the bronchial provocation test was negative.
However, at the time of the test, I was taking a high dose of corticosteroids (four pills a day).
I wonder if this could have affected the test results.
What does the necessity of using a bronchodilator to effectively relieve my cold symptoms indicate? How should I address this issue? I am currently still taking methylprednisolone (2.5 pills a day) and mycophenolate mofetil (180 mg BID).
mimi, 20~29 year old female. Ask Date: 2011/06/26
Dr. Zeng Guosen reply Internal Medicine
Hello, user: The need to use bronchodilators to effectively alleviate discomfort from a cold may indicate respiratory issues, which could be related to chronic inflammation, allergies, or autoimmune diseases.
It is recommended that you consult a pulmonologist for a more detailed examination to clarify your concerns.
Thank you for your question.
Reply Date: 2011/06/26
More Info
Managing cold symptoms and breathing issues in individuals with autoimmune conditions can be quite complex, especially when long-term use of corticosteroids and immunosuppressants is involved. Your experience of increased respiratory discomfort and rapid breathing during colds is not uncommon among patients with autoimmune diseases, particularly those on such medications.
Corticosteroids, like methylprednisolone, are known to suppress the immune system. While this can be beneficial in controlling inflammation and preventing autoimmune flare-ups, it also makes individuals more susceptible to infections, including respiratory infections. When you catch a cold, your body may not respond as robustly as it would in someone with a fully functioning immune system. This can lead to more pronounced symptoms, such as increased shortness of breath and chest discomfort.
The fact that you find relief with a bronchodilator like albuterol (the "備勞喘噴劑" you mentioned) suggests that your symptoms may have an asthmatic component. Even though your bronchial provocation test was negative, the use of corticosteroids can indeed affect the results of such tests, potentially masking underlying hyperreactivity of the airways. This means that while you may not have asthma in a classic sense, your airways could still be sensitive and reactive, particularly when faced with respiratory infections or allergens.
Your elevated IgE and ECP levels indicate some degree of allergic response or inflammation, which could be contributing to your symptoms. In individuals with autoimmune conditions, the interplay between immune dysregulation and respiratory health can be intricate. It's crucial to monitor your symptoms closely and communicate with your healthcare provider about any changes, especially during cold seasons.
Here are some strategies to manage your symptoms effectively:
1. Medication Management: Continue using your bronchodilator as needed. Discuss with your healthcare provider about the possibility of adjusting your corticosteroid dosage during cold seasons or when you are symptomatic. Sometimes, a temporary increase in corticosteroid dosage can help manage inflammation during acute respiratory illnesses.
2. Preventive Measures: Since you are at a higher risk for infections, consider taking preventive measures such as getting vaccinated against influenza and pneumonia if you haven't already. Good hand hygiene and avoiding close contact with sick individuals can also help reduce your risk of catching colds.
3. Monitoring Symptoms: Keep a symptom diary to track your respiratory symptoms, medication use, and any triggers you notice. This information can be invaluable for your healthcare provider in tailoring your treatment plan.
4. Lifestyle Adjustments: Ensure you are maintaining a healthy lifestyle, including a balanced diet, regular exercise (as tolerated), and adequate hydration. These factors can support your overall immune function and respiratory health.
5. Consultation with Specialists: If your symptoms persist or worsen, consider consulting a pulmonologist or an allergist. They can provide further evaluation and management options tailored to your specific situation.
6. Stress Management: Since stress can exacerbate autoimmune conditions and respiratory issues, incorporating stress-reducing techniques such as mindfulness, yoga, or meditation may be beneficial.
In summary, while managing cold symptoms and breathing issues in the context of autoimmune conditions can be challenging, a proactive approach involving medication management, preventive strategies, and lifestyle adjustments can significantly improve your quality of life. Always keep an open line of communication with your healthcare provider to ensure that your treatment plan is optimized for your needs.
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