What to Do If You Received Rubella Vaccine While Early Pregnant? - Obstetrics and Gynecology

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What should I do if I received the German measles vaccine while less than one month pregnant?


Hello, I had my first day of menstruation on August 7.
I took a pregnancy test at Mackay Memorial Hospital on September 1, which came back negative.
Therefore, I received the German measles vaccine.
My menstruation did not arrive on September 7, so I took another pregnancy test on September 15, which indicated that I am already 5 weeks pregnant.
I would like to know if this has any impact on the fetus.
Many international research reports suggest that there is no effect, but my pediatrician mentioned that the subjects of those reports were mostly individuals who received the MMR vaccine in the second or third trimester, so they do not recommend continuing the pregnancy because MMR has the most significant effects in the early stages.
Who should I listen to? Thank you for your help!

NANCY, 30~39 year old female. Ask Date: 2011/09/19

Dr. Zhang Yongxuan reply Obstetrics and Gynecology


During the first trimester of pregnancy (the first three months), it is best to avoid taking medications or receiving injections unless they are lifesaving.

Reply Date: 2011/09/19

More Info


Receiving the rubella vaccine (part of the MMR vaccine, which includes measles, mumps, and rubella) during early pregnancy can understandably cause concern for expectant mothers. However, it's important to clarify the implications based on current medical understanding and research.

Firstly, the MMR vaccine is a live attenuated vaccine, which means it contains a weakened form of the virus. It is generally recommended that women avoid becoming pregnant for at least 28 days after receiving the MMR vaccine. This precaution is due to the theoretical risk of the live virus affecting the developing fetus. However, studies have shown that the risk of congenital rubella syndrome (CRS) or other adverse effects on the fetus from receiving the MMR vaccine during early pregnancy is extremely low.

In your case, you received the rubella vaccine on September 1st, and then discovered you were pregnant on September 15th, which means you were likely already pregnant at the time of vaccination. Research indicates that the incidence of birth defects associated with rubella vaccination during pregnancy is very low. A comprehensive review of cases has shown that there are no significant associations between the MMR vaccine and adverse pregnancy outcomes, particularly when the vaccine is administered before conception or in the early weeks of pregnancy.

Your pediatrician's concerns may stem from the fact that the most critical period for fetal development is during the first trimester, particularly the first 8 weeks. However, the consensus in the medical community is that the benefits of vaccination, especially in preventing rubella, which can cause severe birth defects if a woman contracts the virus during pregnancy, outweigh the risks associated with vaccination during early pregnancy.

If you are feeling anxious about this situation, it is advisable to consult with a healthcare provider who specializes in maternal-fetal medicine. They can provide personalized guidance based on your health history and the specifics of your pregnancy. Regular prenatal care is essential, and your healthcare provider can monitor the development of your baby closely.

In summary, while it is understandable to be concerned about the implications of receiving the rubella vaccine during early pregnancy, the current body of evidence suggests that the risks are minimal. It is crucial to maintain open communication with your healthcare providers and to follow their recommendations for prenatal care. If you have further questions or concerns, do not hesitate to seek additional opinions or support from specialists in maternal health.

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