Timing and Considerations for Chickenpox Vaccine After Measles Immunization - Obstetrics and Gynecology

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Varicella vaccine


Hello Doctor: Currently, I have no antibodies for rubella and varicella.
I received the rubella vaccine on April 30.
How long should I wait to receive the varicella vaccine after the rubella vaccine? How long should I avoid pregnancy after receiving the varicella vaccine? Thank you!

Xiao Ping, 30~39 year old female. Ask Date: 2015/05/26

Dr. Lü Lizheng reply Obstetrics and Gynecology


After receiving the varicella vaccine, it is advised to avoid pregnancy for one month.
It is recommended to space the varicella vaccine and the rubella vaccine by one month before administration.
Sincerely, Lu Lizheng.

Reply Date: 2015/05/26

More Info


When considering the timing for the administration of the chickenpox (varicella) vaccine after receiving the measles, mumps, and rubella (MMR) vaccine, it is essential to understand the immunological implications and recommendations based on current medical guidelines.

The MMR vaccine is a live attenuated vaccine, which means it contains weakened forms of the viruses that cause measles, mumps, and rubella. Similarly, the chickenpox vaccine is also a live attenuated vaccine. When two live vaccines are administered, there is a potential for interference in the immune response if they are given too close together. Therefore, the Centers for Disease Control and Prevention (CDC) recommends that live vaccines, including the MMR and varicella vaccines, should ideally be spaced out by at least 28 days. This spacing helps ensure that the immune system can respond adequately to each vaccine without interference.

In your case, since you received the MMR vaccine on April 30, you would typically wait at least 28 days before administering the chickenpox vaccine. This means that you could consider getting the chickenpox vaccine around May 28 or later. However, if there are specific health considerations or if you have any underlying conditions, it is always best to consult with your healthcare provider for personalized advice.

Regarding the question of contraception after receiving the chickenpox vaccine, it is important to note that the varicella vaccine is not recommended for pregnant women due to the potential risk to the fetus. Therefore, if you are of childbearing age and are planning to receive the chickenpox vaccine, it is advised to avoid becoming pregnant for at least one month after vaccination. This precaution is in place because the vaccine contains live attenuated virus, and while the risk is considered low, it is better to err on the side of caution.

In summary, after receiving the MMR vaccine on April 30, you should wait at least 28 days before getting the chickenpox vaccine, which would be around May 28. Additionally, if you receive the chickenpox vaccine, it is advisable to avoid pregnancy for at least one month following vaccination. Always consult with your healthcare provider for the most accurate and personalized medical advice.

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