the Risks of Early Vaccination for Chickenpox and Measles - Pediatrics

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Varicella and Measles Vaccines


Hello Dr.
Hsiao, on the afternoon of April 8, 2011, I took my just one-year-old son to the well-child clinic.
Since he had taken antihistamine steroids on April 1, 2011, the doctor advised me to wait one month before administering vaccines (varicella, measles, and pneumococcal conjugate vaccine).
I would like to ask Dr.
Hsiao, if the vaccines are administered earlier, what adverse reactions might occur in my child? Also, do you agree with the recommendation to delay the vaccination for another month? Thank you for taking the time to respond.
Thank you, April 11, 2011.

Jack, 30~39 year old female. Ask Date: 2011/04/11

Dr. Xiao Kaiwen reply Pediatrics


The health department lists individuals currently undergoing treatment with corticosteroids (steroids) as contraindicated for vaccination.
I believe that those using low-dose steroids for a short duration (such as for urticaria) should be able to receive the vaccine after discontinuing the medication for one week, as the body would have metabolized it by then.

Reply Date: 2011/04/11

More Info


When considering the risks associated with early vaccination for chickenpox and measles, it is essential to understand both the nature of these vaccines and the potential implications of administering them outside the recommended schedule. Vaccination is a critical public health measure that helps prevent the spread of infectious diseases, and both the chickenpox (varicella) and measles vaccines are typically administered according to specific timelines to ensure optimal immune response and protection.

The chickenpox vaccine is usually given to children between 12 to 15 months of age, with a second dose recommended between 4 to 6 years of age. The measles, mumps, and rubella (MMR) vaccine is also administered in a similar timeframe, typically at 12 to 15 months, with a second dose between 4 to 6 years. These timelines are based on extensive research that has determined the best age for children to develop a robust immune response to these vaccines.

If your child has recently taken corticosteroids for an allergic reaction, it is crucial to consider how these medications can affect the immune system. Corticosteroids can suppress the immune response, which may lead to a reduced effectiveness of the vaccine if administered too soon after steroid treatment. This is why the physician recommended waiting for a month after the steroid treatment before proceeding with vaccinations. Administering the vaccine while the immune system is still compromised could result in inadequate protection against these diseases.

In terms of potential adverse reactions from early vaccination, while most children tolerate vaccines well, there are risks associated with administering them when the immune system is not fully prepared. Possible adverse reactions can include a higher likelihood of mild side effects such as fever, rash, or irritability. In rare cases, there could be more severe reactions, but these are generally associated with underlying health conditions or improper timing of the vaccine.

Delaying the vaccination for a month, as suggested by your physician, is a prudent approach. This allows your child's immune system to recover fully from the effects of the corticosteroids, ensuring that the vaccines can elicit a strong and effective immune response. It is always better to err on the side of caution when it comes to vaccinations, especially in young children whose immune systems are still developing.

In summary, while early vaccination may seem like a way to provide protection sooner, it is essential to adhere to the recommended vaccination schedule, particularly in the context of recent steroid use. Waiting for a month, as your physician advised, is the best course of action to ensure that your child receives the full benefits of the vaccines without unnecessary risks. Always consult with your healthcare provider for personalized advice based on your child's health history and current condition.

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