the Sudden Increase of Liver Hemangiomas: A Patient's Concern - Gastroenterology and Hepatology

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Hepatic hemangioma proliferation issues?


Hello, doctor.
I discovered a hemangioma about 3 cm in size during my health checkup two years ago.
This year, my checkup revealed four liver tumors (three new ones), including the one that has grown to 3.5 cm.
I asked the screening physician if they were also hemangiomas, but the physician said that ultrasound cannot determine that and recommended I visit a larger hospital for further evaluation.
Recently, I went to the National Taiwan University Hospital branch for follow-up, and the physician's ultrasound examination suggested that they appear to be hemangiomas.
I do not smoke or drink alcohol, and I do not have hepatitis C or B; however, I do have fatty liver and roughness on the liver surface.
CEA levels are currently normal.
I would like to ask if it is possible for hemangiomas to suddenly increase in number like this, especially since each one is larger than 1.5 cm.
I can't shake the feeling that something is off...

RL, 40~49 year old female. Ask Date: 2011/11/09

Dr. Chen Shidian reply Gastroenterology and Hepatology


Dear Mr./Ms.
RL: Based on your description, if you suddenly have three additional vascular tumors larger than 1.5 cm within a year, we recommend that you arrange for a contrast-enhanced CT scan at a nearby large hospital to further confirm whether they are indeed vascular tumors.
Thank you for your inquiry! Changhua Hospital cares about your health!

Reply Date: 2011/11/09

More Info


Liver hemangiomas are the most common benign tumors of the liver, often discovered incidentally during imaging studies such as ultrasound or CT scans. Your concern regarding the sudden increase in the number of hemangiomas and their size is understandable, especially given your previous health checks and the recent findings.
To address your question about whether liver hemangiomas can suddenly increase in number, it is important to note that while these tumors are typically stable and grow very slowly, there are instances where new hemangiomas can develop. The exact cause of hemangioma formation is not well understood, but they are thought to be congenital vascular malformations. Factors such as hormonal influences, particularly estrogen, may play a role in their growth, which is why they are more common in women.
In your case, the increase from one hemangioma to four, with sizes greater than 1.5 cm, is unusual but not impossible. It is essential to differentiate between true new hemangiomas and the possibility of misinterpretation of existing lesions on imaging studies. Ultrasound may not always provide definitive answers, and further imaging, such as a contrast-enhanced MRI or a dynamic CT scan, may be necessary to characterize these lesions accurately. The dynamic liver triphasic imaging protocol you mentioned in your earlier inquiry refers to a specific CT imaging technique that captures the liver's vascularity in three phases: arterial, portal venous, and delayed phases. This method provides a clearer picture of liver lesions and helps in distinguishing hemangiomas from other types of liver tumors.

Regarding your concern about the growth rate of hemangiomas, they generally grow very slowly, if at all. Most hemangiomas do not require treatment unless they cause symptoms or complications, which is rare. The typical management approach is to monitor the lesions with periodic imaging, usually every 6 to 12 months, depending on the size and characteristics of the hemangiomas.
In terms of lifestyle considerations, since you mentioned having fatty liver, it is advisable to maintain a healthy diet, engage in regular physical activity, and avoid alcohol consumption. These measures can help manage your liver health and potentially reduce the risk of further complications.

If you are feeling anxious about the situation, it is crucial to communicate openly with your healthcare provider. They can provide reassurance, explain the nature of hemangiomas, and discuss the appropriate follow-up plan tailored to your specific case. Remember, while the presence of multiple hemangiomas may seem concerning, they are typically benign and manageable with regular monitoring.
In summary, while the sudden increase in the number of liver hemangiomas is not typical, it is not entirely out of the realm of possibility. Further imaging studies may be warranted to ensure accurate diagnosis and management. Regular follow-ups and a healthy lifestyle are key components in managing your liver health.

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