Can I Have a Healthy Baby After Taking Conquer Tab 1200mg During Pregnancy?

Is it safe to take Conquer Tab 1200mg while pregnant? Will the child be born healthy?

Hello Doctor, I am Wu Meifeng's mother.
I recently learned that I successfully conceived in February and am now about one month pregnant.
However, I was unaware of my pregnancy while taking an antiparasitic medication.
I took Conquer Tab 1200mg for two weeks.
Later, my gynecologist advised me against carrying this pregnancy to term, but if I insist on continuing, they suggested I consult a maternal-fetal medicine specialist.
Could you please inform me about the potential effects on the baby and what tests or evaluations I should undergo to ensure a healthy pregnancy? I am very worried about the possibility of having an unhealthy child.
Thank you for your help.

Wu Mei-feng, 30~39 year old female. Ask Date: 2012/03/13

Dr. Chen Ming reply Rare Disease

The medication Mebendazole is indeed not very safe from a pharmacological standpoint.
Please consult a physician specializing in genetic counseling in the obstetrics and gynecology department at a nearby medical center.
Personally, I also believe it is not very safe.
If you wish to continue the pregnancy, it is essential to have thorough prenatal check-ups.
This is a response from Dr.
Ming Chen, Director of the Department of Genetic Medicine at Chang Gung Memorial Hospital.

Reply Date: 2012/03/13

More Info

Taking Conquer Tab (Mebendazole) during early pregnancy raises valid concerns regarding fetal health. Mebendazole is an anthelmintic medication primarily used to treat parasitic worm infections. While it is generally considered safe for use in non-pregnant individuals, its safety profile during pregnancy is less clear, particularly in the first trimester when fetal organ development is occurring.

The primary concern with using Mebendazole during pregnancy is its potential teratogenic effects, which means it could potentially cause developmental abnormalities in the fetus. Although animal studies have not shown significant risks, human data is limited. The FDA classifies Mebendazole as a Category C drug, indicating that risk cannot be ruled out. This means that while there may not be conclusive evidence of harm, the potential risks should be carefully weighed against the benefits of treatment.

Given your situation, it is crucial to consult with a healthcare provider who specializes in maternal-fetal medicine or genetic counseling. They can provide personalized advice based on your medical history and the specifics of your pregnancy. Here are some steps and considerations that may be recommended:
1. Genetic Counseling: This can help assess the potential risks to your baby based on your medication use and family history. Genetic counselors can provide information about possible tests and screenings.

2. Ultrasound Monitoring: Regular ultrasounds can help monitor fetal development and detect any abnormalities early on. This is particularly important if there are concerns about the effects of the medication.

3. Prenatal Screening: Depending on the recommendations from your healthcare provider, you may be offered additional prenatal screening tests, such as non-invasive prenatal testing (NIPT) or chorionic villus sampling (CVS), to assess the risk of genetic conditions.

4. Nutritional Support: Ensure you are receiving adequate nutrition, as this is vital for fetal development. Prenatal vitamins, particularly those containing folic acid, are essential to reduce the risk of neural tube defects.

5. Mental Health Support: It’s understandable to feel anxious about the health of your baby. Consider seeking support from mental health professionals or support groups for expectant mothers.

6. Follow-Up Care: Regular prenatal visits are crucial. Your healthcare provider will monitor your pregnancy closely and address any concerns that arise.

While it is natural to worry about the health of your baby after taking a medication during early pregnancy, many women have healthy pregnancies and babies despite similar circumstances. The key is to maintain open communication with your healthcare team, follow their recommendations, and stay informed about your options. Remember, early intervention and monitoring can significantly improve outcomes.

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