Side Effects of Mycomb Cream and Betaderm Cream - Pharmacology

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Side effects of two medications?


Are there any side effects associated with MYCOMB CREAM and BETADERM CREAM? If so, how long do they typically last? The areas where the medication was applied have shown significant improvement, but small red spots have started to appear on my body and limbs, which itch when rubbed.
Additionally, my face and hairline are experiencing dryness, itching, peeling, and a stinging sensation.
Could these symptoms be related to the two medications mentioned above? I have already stopped applying them; is there a quick relief method for the side effects?

haha, 20~29 year old female. Ask Date: 2012/03/29

Dr. Hou Fangmin reply Pharmacology


Hello:
1.
The MYCOMB CREAM you mentioned contains the following ingredients per gram: Miconazole 100,000 units, Neomycin 2.5 mg, Gramicidin 0.25 mg, and Triamcinolone Acetonide 1 mg.
It has antibiotic and antifungal properties and is used to treat eczema, allergic and inflammatory skin conditions, as well as secondary bacterial or fungal infections (such as candidiasis).
It also contains a corticosteroid, and potential side effects include rash and skin irritation.
2.
BETADERM CREAM contains Betamethasone 0.1 mg and Gentamicin 1 mg.
It includes a corticosteroid and an antibiotic, making it effective for treating various allergic skin symptoms.
The antibiotic Gentamicin is effective against both primary and secondary bacterial skin infections.
Side effects may include localized burning, itching, rash, and dryness.
These side effects typically resolve after discontinuing the medication for a period.
If the pain persists, it is advisable to consult a physician.
Antihistamines, available in oral and injectable forms, can provide relief; the injectable form acts quickly but requires a physician's prescription.
Fungal infections of the skin can sometimes be difficult to distinguish from other inflammatory skin conditions, so caution is advised when using ointments.

Does this answer your questions? Lastly, I wish you good health and peace of mind.

Reply Date: 2012/03/29

More Info


Mycomb Cream and Betaderm Cream are both topical medications commonly used to treat various skin conditions, including eczema, dermatitis, and secondary bacterial or fungal infections. However, like all medications, they can have side effects. Understanding these side effects and how to manage them is crucial for effective treatment and patient comfort.

Mycomb Cream contains a combination of ingredients: Miconazole (an antifungal), Neomycin (an antibiotic), Gramicidin (another antibiotic), and Triamcinolone Acetonide (a corticosteroid). The side effects associated with Mycomb Cream can include:
1. Skin Irritation: This can manifest as redness, burning, or stinging at the application site.

2. Allergic Reactions: Some individuals may develop rashes or hives, particularly if they are sensitive to any of the components.

3. Dryness and Peeling: The corticosteroid component can lead to skin thinning and dryness, especially with prolonged use.

4. Folliculitis: In some cases, the use of topical antibiotics can lead to inflammation of hair follicles.

Betaderm Cream, on the other hand, contains Betamethasone (a corticosteroid) and Gentamicin (an antibiotic). Its side effects may include:
1. Local Irritation: Similar to Mycomb, patients may experience burning, itching, or redness at the site of application.

2. Dryness and Peeling: The corticosteroid can cause the skin to become dry and flaky.

3. Systemic Absorption: With prolonged use, especially over large areas of the body or under occlusive dressings, there is a risk of systemic absorption leading to side effects associated with corticosteroids, such as adrenal suppression.

4. Allergic Reactions: As with Mycomb, some patients may develop allergic reactions to the ingredients.

In your case, the symptoms you describe—small red spots, itching, dryness, peeling, and stinging—could indeed be related to the use of either Mycomb Cream or Betaderm Cream. These symptoms may indicate a localized reaction to the medication, particularly if they developed after starting treatment. The duration of these side effects can vary; typically, they may resolve within a few days to weeks after discontinuing the medication, but this can depend on individual skin sensitivity and the extent of the reaction.

To manage these side effects, here are some recommendations:
1. Discontinue Use: Since you have already stopped applying the creams, this is the first step. Avoid using any topical medications until the skin has healed.

2. Moisturizers: Apply a gentle, fragrance-free moisturizer to help soothe the skin and combat dryness. Look for products that contain ceramides or hyaluronic acid, which can help restore the skin barrier.

3. Cool Compresses: If itching is severe, applying a cool, damp cloth to the affected areas can provide temporary relief.

4. Antihistamines: Over-the-counter oral antihistamines can help reduce itching and discomfort.

5. Consult a Dermatologist: If symptoms persist or worsen, it’s essential to consult a healthcare provider. They may recommend alternative treatments or prescribe medications to alleviate the symptoms.

In conclusion, while both Mycomb Cream and Betaderm Cream can be effective for treating skin conditions, they can also cause side effects that may lead to discomfort. Monitoring your skin's response to these medications and seeking medical advice when adverse reactions occur is vital for ensuring safe and effective treatment.

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