Lymph Node Tuberculosis: Treatment and Concerns - Otolaryngology

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Lymphatic tuberculosis


I have some questions for the doctor.
In early March of this year, I had swollen lymph nodes on the left side of my neck and went to the hospital for examination.
A fine needle aspiration revealed the presence of pus, and it was determined to be a tuberculosis infection.
After two months of medication, the lymph nodes on the right side of my neck also started to swell.
I would like to ask the doctor two questions: 1.
Why is the right side still swelling after two months of medication, especially since the hospital indicated that the bacteria are sensitive to the drugs? 2.
The swollen area on the right side is now approximately 8 to 9 centimeters in size.
After three months of medication, the right lymph node has changed from small and firm to large and soft.
Should I continue taking the medication and wait for the swelling to subside naturally, or is drainage necessary?

Chen Jieke, 20~29 year old female. Ask Date: 2012/06/03

Dr. Xu Jiazhen reply Otolaryngology


Hello: The incidence of cervical lymphadenitis due to tuberculosis has been increasing year by year in developing countries.
If your diagnosis is confirmed, it is essential to undergo treatment to avoid complications.
First-line anti-tuberculosis medications may not always be effective, and sometimes second-line drugs are needed.
If there is a local increase in size, partial neck lymphadenectomy may be considered to help control the spread of the disease.
This is not an easy condition to treat, so please closely cooperate with your specialist.
Sincerely, Hsu Chia-Chen.

Reply Date: 2012/06/03

More Info


Lymph node tuberculosis, also known as tuberculous lymphadenitis, is a form of extrapulmonary tuberculosis that primarily affects the lymph nodes. It is caused by Mycobacterium tuberculosis, the same bacterium responsible for pulmonary tuberculosis. The condition often presents as swollen lymph nodes, typically in the neck, and can lead to the formation of abscesses filled with pus.
In your case, it is concerning that after two months of treatment, you are experiencing swelling in the right lymph node, especially since the initial diagnosis was confirmed as a tuberculosis infection. There are a few important points to consider regarding your situation.

1. Why is the right lymph node swelling despite two months of treatment?
The persistence or recurrence of lymph node swelling during treatment can be attributed to several factors. First, it is essential to understand that while the medication may be effective against the bacteria, the immune response and the body's healing process can take time. The swelling may be due to ongoing inflammation as the body fights the infection. Additionally, there may be a delay in the resolution of the lymphadenopathy, even when the bacteria are sensitive to the drugs. In some cases, the initial treatment may not be sufficient to fully eradicate the infection, leading to the involvement of other lymph nodes.
Furthermore, it is also possible that the right lymph node was already affected before the treatment began but was not yet noticeable. In some cases, the bacteria can remain dormant in other lymph nodes, leading to delayed symptoms.
2. What should be done about the right lymph node that has swollen to 8-9 cm?
The size of the lymph node and its characteristics (hardness, softness) are important clinical indicators. A lymph node that has increased in size and has changed in consistency (from hard to soft) may indicate that it is undergoing a process of necrosis or abscess formation. In such cases, it is crucial to evaluate whether the lymph node is forming an abscess that may require drainage.
Continuing the anti-tuberculosis medication is essential, as it helps in controlling the infection. However, if the lymph node is significantly enlarged and symptomatic, or if there are signs of abscess formation (such as fever, pain, or drainage), a surgical consultation may be warranted. An ultrasound or CT scan may be helpful to assess the lymph node's characteristics further and determine if drainage is necessary.

In summary, while it is not uncommon for lymph nodes to remain swollen or even swell further during the early stages of treatment for tuberculosis, it is crucial to monitor the situation closely. Regular follow-ups with your healthcare provider are essential to assess the response to treatment and to decide on further management, including the possibility of drainage if an abscess is suspected.
In conclusion, continue your prescribed medication, maintain close communication with your healthcare provider, and seek further evaluation if the swelling persists or worsens. Tuberculosis treatment can be complex and requires careful monitoring to ensure effective resolution of the infection.

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