Concerns About Mydriatic Use in High Myopia Patients - Ophthalmology

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Pupil-dilating agent issues?


Dear Dr.
Gao,
Due to my high myopia (left eye: -10.50, right eye: -13.00), I have experienced a progressive increase of 200 degrees in my right eye over the past three years (originally -11.00).
I have been using a short-acting cycloplegic agent for about a year and a half, and I have the following questions:
1.
If I stop using the cycloplegic agent, will it lead to an increase in my vision?
2.
Does prolonged use of the cycloplegic agent contribute to dry eye syndrome?
3.
With long-term use of the cycloplegic agent, could the preservatives in it cause harm to my eyes?

angela, 20~29 year old female. Ask Date: 2012/07/09

Dr. Gao Pilin reply Ophthalmology


Hello: In response to your questions, here are the answers: 1.
If you use a dilating agent for a period of time and then stop, it may lead to an increase in refractive error.
This is because the dilating agent relaxes the eye muscles, and if you stop using it, your eyes may strain again, resulting in an increase in prescription.
2.
Prolonged use of dilating agents is not likely to cause dry eye syndrome.
3.
Most eye medications contain preservatives, and when used as directed, they should not cause harm to the eyes.
Using a dilating agent once a day will not cause any damage.
Thank you for your inquiry.

Reply Date: 2012/07/09

More Info


When it comes to the use of mydriatic agents in patients with high myopia, there are several important considerations to keep in mind. High myopia, defined as a refractive error greater than -6.00 diopters, can lead to various ocular complications, including retinal detachment, glaucoma, and cataracts. Therefore, the use of mydriatic agents, which are commonly used to dilate the pupils for examination purposes, must be approached with caution.

1. Stopping Mydriatic Use and Vision Changes: If you stop using mydriatic agents, it is unlikely that your vision will significantly improve or worsen solely due to the cessation of these drops. Mydriatic agents are typically used for diagnostic purposes and do not directly alter the refractive error of the eye. However, if the drops were being used to manage specific conditions related to your high myopia, such as controlling intraocular pressure or facilitating better examination of the retina, stopping them could potentially lead to a lack of monitoring or treatment for those conditions. It is essential to discuss with your ophthalmologist the reasons for using these drops and the potential implications of discontinuing them.

2. Dry Eye Syndrome from Prolonged Use: Long-term use of mydriatic agents can contribute to dry eye symptoms. Mydriatic drops often contain preservatives, which can be irritating to the ocular surface, especially with frequent use. This irritation can lead to symptoms of dryness, discomfort, and even exacerbate existing dry eye conditions. If you are experiencing symptoms of dry eyes, it is advisable to discuss alternative options with your eye care provider, such as preservative-free formulations or artificial tears to help alleviate dryness.

3. Potential Harm from Preservatives: Many mydriatic agents contain preservatives, such as benzalkonium chloride, which can be toxic to the corneal epithelium with prolonged exposure. Chronic use of these preservatives can lead to ocular surface disease, which may manifest as discomfort, redness, and visual disturbances. If you have been using mydriatic drops for an extended period, it is crucial to evaluate the formulation you are using and consider switching to preservative-free options if available. Your ophthalmologist can provide guidance on the best practices for managing your eye health while minimizing the risk of adverse effects from medications.

In summary, while mydriatic agents are useful for certain diagnostic and therapeutic purposes, their long-term use in patients with high myopia should be carefully monitored. It is essential to maintain open communication with your eye care provider regarding any concerns you have about the use of these medications, especially in the context of your high myopia. Regular eye examinations and discussions about your treatment plan can help ensure that you are receiving the best care tailored to your specific needs.

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