How Soon to Test for Antibodies After German Measles Vaccination? - Family Medicine

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German measles vaccine


Hello, doctor: How long after receiving the German measles vaccine can I check for the presence of antibodies? If antibodies are not produced, should I receive a booster shot? Thank you!

Bubu, 20~29 year old female. Ask Date: 2012/07/28

Dr. Liao Yaopan reply Family Medicine


Hello, regarding the German measles vaccine, I would like to know if it is intended for children or if it is an additional dose for women of childbearing age.
According to the current vaccination schedule for young children, there are two doses of the measles, mumps, and rubella (MMR) vaccine administered before entering elementary school, which is a more complete vaccination schedule.
If it is for women of childbearing age, an additional dose of the rubella vaccine may be given.
Generally, most individuals can develop antibodies about a month after vaccination.
Whether a booster shot is necessary can be further evaluated by a physician.
Thank you for your inquiry.
Changhua Hospital cares about you.

Reply Date: 2012/07/28

More Info


After receiving the German measles vaccine, also known as the rubella vaccine, it is generally recommended to wait at least four weeks before testing for antibodies. This timeframe allows your immune system sufficient time to respond to the vaccine and produce antibodies. The rubella vaccine is highly effective, with an efficacy rate of about 95%, meaning that the vast majority of individuals will develop immunity after vaccination.

The Centers for Disease Control and Prevention (CDC) does not routinely recommend antibody testing after vaccination unless there are specific concerns, such as a history of immunosuppression or if the individual is planning to become pregnant shortly after vaccination. In most cases, if you have received the recommended doses of the rubella vaccine, you can be confident in your immunity without the need for testing.

If an antibody test is performed and it shows that you have not developed antibodies, the CDC does not recommend a routine revaccination. However, if you have concerns about your immunity or if you are in a high-risk group, it may be advisable to consult with a healthcare provider. They can assess your individual situation and determine if a booster dose is necessary.

In terms of pregnancy, it is important to note that women are advised to avoid becoming pregnant for at least four weeks after receiving the rubella vaccine. This precaution is due to the theoretical risk of the live attenuated virus affecting a developing fetus. Therefore, if you are planning to conceive, it is best to wait until after this period has passed.

In summary, after receiving the German measles vaccine, you should wait at least four weeks before testing for antibodies. If the test shows no antibodies, revaccination is not typically recommended unless there are specific medical reasons. Always consult with your healthcare provider for personalized advice, especially if you are considering pregnancy or have other health concerns.

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