Will Long-Term Medication Use Affect My Baby's Health? - Obstetrics and Gynecology

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I wonder if it will affect the baby's health?


Hello Dr.
Cheng, I have been married for a year, and due to health issues, I did not want to get pregnant in the short term.
However, I am currently pregnant.
My last menstrual period was on July 31.
I have been taking antihistamines for a year due to persistent urticaria, and I also have a long-standing issue with headaches, for which I frequently take pain relievers.
I am concerned whether this will affect the health of my baby.

Chen, 30~39 year old female. Ask Date: 2000/09/19

Dr. Li Guanghan reply Obstetrics and Gynecology


If your last menstrual period indicates that you are 7 weeks pregnant, taking medication during weeks 6 to 8 may affect the fetus, as antihistamines have shown teratogenic effects in animal studies.
However, second and third-generation antihistamines are generally considered safer for the fetus.
You should consult the physician who prescribed the medication for further advice.
Additionally, if you are taking acetaminophen, it is relatively safe for the fetus, while other pain relievers, such as aspirin, may be harmful.

Reply Date: 2000/09/19

More Info


When considering the impact of long-term medication use on your baby's health, especially during pregnancy, it's essential to understand the specific medications involved and their potential effects. Based on your description, you have been taking antihistamines for urticaria (hives) and pain relievers for chronic headaches.
1. Antihistamines: The safety of antihistamines during pregnancy can vary depending on the specific type. First-generation antihistamines, such as diphenhydramine (Benadryl), have been associated with some risks, while second-generation antihistamines, like cetirizine (Zyrtec) and loratadine (Claritin), are generally considered safer. Some studies suggest that certain antihistamines may have a low risk of causing birth defects, but it's crucial to consult your healthcare provider about the specific antihistamine you are using. They can provide guidance based on the latest research and your individual health needs.

2. Pain Relievers: The type of pain reliever you are using is also critical. Acetaminophen (Tylenol) is typically considered safe during pregnancy when used as directed. However, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin are generally advised against, especially in the third trimester, due to potential risks to the fetus. Long-term use of NSAIDs can lead to complications such as premature closure of the ductus arteriosus, a vital blood vessel in the fetus.

3. Potential Effects on the Baby: If you have been taking medications that are deemed safe during pregnancy, the risks to your baby are likely minimal. However, if you are using medications that have known risks, it is essential to discuss these with your healthcare provider. They can help assess the benefits versus risks and may suggest alternative treatments that are safer for both you and your baby.

4. Consultation with Healthcare Providers: It is crucial to have open communication with your healthcare provider about all medications you are taking. They can help you weigh the risks and benefits and may recommend adjustments to your treatment plan to ensure the best outcomes for both you and your baby.

5. Monitoring and Follow-Up: If you have concerns about the effects of your medications, regular monitoring during your pregnancy can help identify any potential issues early on. Your healthcare provider may suggest additional screenings or tests to ensure your baby's health.

In summary, while long-term medication use can potentially affect your baby's health, the extent of that impact largely depends on the specific medications involved. Always consult with your healthcare provider for personalized advice and to explore safer alternatives if necessary. They can provide the most accurate information based on your medical history and the medications you are taking. Your health and the health of your baby are paramount, and proactive management of your medications during pregnancy is essential.

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