the Difference Between Mood Stabilizers and Antidepressants - Psychiatry

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Mood stabilizers


Hello, Doctor: I would like to ask if mood stabilizers and antidepressants mean the same thing? The doctor prescribed me You-Jet, half a tablet daily, but I only take it when I feel off; sometimes when I feel better, I don't take it.
Would this be worse? Because I sometimes feel like I want to rely on my own strength, and I feel like this is like a placebo.
Thank you.

chia, 30~39 year old female. Ask Date: 2012/12/30

Dr. Ding Shuyan reply Psychiatry


Hello! First of all, if we are not healthcare professionals, our understanding of medical terminology can sometimes be influenced by incorrect information from others or the media.
For example, I have noticed that the media's portrayal of bipolar disorder differs from the clinical definition provided by psychiatrists, and this misunderstanding affects many people.
Assuming that the term "mood stabilizers" you mentioned aligns with medical terminology, it is indeed a different category from antidepressants.
Generally, it refers to antipsychotic medications and anxiolytic or sedative drugs.

The medication You-Jet does not have an immediate pharmacological effect; it requires daily administration, and its therapeutic effects typically become noticeable after about two to three weeks, provided that the individual’s body responds to the medication.
Your current method of taking the medication based on how you feel and only when necessary is likely to be ineffective.
If you do experience any effects, they may either be due to a placebo effect or a misperception of improvement caused by the medication's side effects.

We all desire freedom and do not want to feel constrained, which is understandable.
Taking medication daily can feel like losing self-control and being governed by the medication.
However, some conditions cannot be managed solely by willpower; sometimes, relying on religion or a higher power may not yield quick results either.
In such cases, medication can be a relatively faster and more reliable option, and following a physician's prescription becomes the wisest course of action.

Psychiatric symptoms are often abstract and not as objectively evident as physical ailments like a cold or fever, which can lead to blind spots in our self-assessment.
We may sometimes feel that we are not ill or question the effectiveness of the medication, finding it cumbersome without knowing what to do.
My advice is to trust the recommendations of professional physicians.
If you cannot trust your current doctor, it is acceptable to seek another opinion.
In any case, it is essential to have faith in a physician and collaborate with them, as this approach is much more reliable than relying solely on oneself.
Wishing you good mental and physical health!

Reply Date: 2012/12/30

More Info


Understanding the difference between mood stabilizers and antidepressants is crucial for anyone dealing with mental health issues. While both types of medications are used to treat mood disorders, they serve different purposes and work through different mechanisms in the brain.

Mood Stabilizers vs. Antidepressants
1. Definitions and Uses:
- Mood Stabilizers: These medications are primarily used to treat mood disorders, particularly bipolar disorder. They help to stabilize mood swings and prevent the extreme highs (mania) and lows (depression) associated with this condition. Common mood stabilizers include lithium, valproate, and lamotrigine.

- Antidepressants: These are primarily used to treat depression and anxiety disorders. They work by altering the balance of neurotransmitters in the brain, particularly serotonin, norepinephrine, and dopamine. Common classes of antidepressants include selective serotonin reuptake inhibitors (SSRIs) like Zoloft and Prozac, and serotonin-norepinephrine reuptake inhibitors (SNRIs) like Effexor.

2. Mechanisms of Action:
- Mood Stabilizers: The exact mechanism of action for mood stabilizers is not fully understood, but they are thought to affect neurotransmitter release and receptor sensitivity, helping to stabilize mood fluctuations.

- Antidepressants: These medications primarily increase the levels of certain neurotransmitters in the brain. For example, SSRIs block the reuptake of serotonin, making more serotonin available in the synaptic cleft, which can improve mood and alleviate depressive symptoms.

3. Side Effects:
- Both mood stabilizers and antidepressants can have side effects, but they differ. Mood stabilizers can cause weight gain, tremors, and gastrointestinal issues, while antidepressants may lead to sexual dysfunction, weight changes, and insomnia. It’s essential to discuss potential side effects with your healthcare provider.

4. Treatment Approach:
- When treating mood disorders, healthcare providers often take a comprehensive approach that may involve both mood stabilizers and antidepressants, depending on the individual’s symptoms and diagnosis. For instance, a person with bipolar disorder may be prescribed a mood stabilizer to manage manic episodes and an antidepressant to address depressive symptoms.

Your Current Medication: You-Jet
You mentioned that you are taking You-Jet (which contains the active ingredient lorazepam) as a mood stabilizer. It’s important to understand that lorazepam is primarily an anxiolytic (anti-anxiety medication) and can also have sedative effects. It is not a mood stabilizer in the traditional sense but can help manage anxiety symptoms that may accompany mood disorders.

Regarding your concern about taking the medication only when you feel "off," it’s crucial to follow your doctor’s instructions. Medications like You-Jet are often most effective when taken consistently, as they require time to build up in your system and exert their full effects. Taking medication sporadically may lead to fluctuations in your mood and anxiety levels, which could make you feel worse over time.

The Importance of Consistency and Professional Guidance
While it’s natural to want to rely on your own strength to manage your mood, mental health conditions often require a combination of self-care strategies and medical intervention. If you feel that the medication is not working or if you are experiencing side effects, it’s essential to communicate this with your healthcare provider. They can help adjust your treatment plan, whether that means changing the dosage, switching medications, or incorporating therapy.

In conclusion, understanding the differences between mood stabilizers and antidepressants can empower you to make informed decisions about your treatment. Always consult with your healthcare provider before making any changes to your medication regimen, and remember that managing mental health is a journey that often requires professional support.

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