Enlarged Lymph Nodes: Concerns and Next Steps - Oncology

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Left axillary lymphadenopathy?


Hello Doctor,
I would like to ask you about my medical condition.
Currently, I have been experiencing enlarged lymph nodes in my left armpit for about three months.
I have undergone an ultrasound, chest X-ray, blood tests, and urine tests.
The ultrasound showed a size of approximately 1.80 x 0.6 cm with a clear outline and no adhesion.
After reviewing these reports, the doctors told me there were no significant issues.

One morning, I woke up with a warm, painful sensation in my left armpit and discovered a soft lump.
I then went to a large hospital for further examination, and the results confirmed lymphadenopathy.
The doctor prescribed antibiotics for about a week, and the pain subsided, but the lymph node felt harder, which made me anxious.
After finishing the first week of antibiotics, I returned for a follow-up, and the doctor said I did not need to continue the medication.

A couple of days later, I started experiencing swelling and inflammation in my left arm, which extended to my armpit, accompanied by a red line.
When I showed this to the doctor, he said it was inflammation of the lymphatic system.
After a few days, that line developed bruising, but the swelling persisted.
The doctor then prescribed another three weeks of antibiotics.
Currently, the swelling has improved, but the lymph node is still present, and it has been about three months.

I am quite troubled by this situation because the doctor mentioned that I would need to be monitored every three months to check for any enlargement and does not favor invasive treatments.
However, I am very anxious because I have read many articles about similar conditions, which can range from benign to serious.
I am having trouble sleeping every day, worrying that it might grow larger.

Do you have any clinical experience or different opinions on this matter? I am concerned that it could be something serious.
Is there a necessity for a biopsy or aspiration?

gǒu gǒu, 20~29 year old female. Ask Date: 2013/04/03

Dr. Fan Sheng reply Oncology


Hello, regarding the symptoms, they appear to be more indicative of an infection rather than a tumor.
You can follow your veterinarian's advice for monitoring.
Do you have any cats at home? Have you been scratched by a cat in the past three months? Wishing you a speedy recovery.

Reply Date: 2013/04/03

More Info


Understanding enlarged lymph nodes can be a source of anxiety for many patients, especially when there are accompanying symptoms such as pain, swelling, or changes in texture. In your case, the left axillary lymph node has been enlarged for about three months, and you have undergone several diagnostic tests, including ultrasound, chest X-ray, and blood tests, all of which have not indicated any serious issues. The lymph node measures approximately 1.80 x 0.6 cm, has a clear outline, and is not fixed to surrounding tissues, which are generally reassuring signs.

The presence of pain and the sensation of heat in the lymph node, followed by the development of swelling in your left arm, suggests that there may have been some inflammatory process at play. This could be due to an infection, which is a common cause of lymphadenopathy (enlarged lymph nodes). The fact that your doctor prescribed antibiotics and the pain subsided indicates that they were addressing a potential infection. However, the persistence of the enlarged lymph node, despite the resolution of pain, is understandably concerning for you.

In clinical practice, lymph nodes can become enlarged for various reasons, including infections, inflammatory conditions, and malignancies. The key factors that guide further evaluation include the duration of enlargement, associated symptoms, and the characteristics of the lymph node itself. In your case, the lymph node has been enlarged for three months, which is a significant duration, but it has not shown signs of malignancy based on imaging and physical examination.

Your doctor’s recommendation to follow up every three months is a common approach in cases of benign lymphadenopathy. This allows for monitoring any changes in size or characteristics of the lymph node over time. If the lymph node were to increase in size, become fixed, or if you develop new symptoms, further investigation, such as a biopsy or fine-needle aspiration, may be warranted.

It is important to note that while the internet can provide a wealth of information, it can also lead to unnecessary anxiety. Many benign conditions can cause lymphadenopathy, and the majority of enlarged lymph nodes are not cancerous. The fact that your healthcare providers have not expressed concern about the lymph node's characteristics is a positive sign.

If you are feeling particularly anxious about the situation, it may be beneficial to discuss your concerns with your healthcare provider. They can provide reassurance, explain the rationale behind the monitoring plan, and discuss the potential need for further testing if your condition changes. Additionally, if you feel that your symptoms are worsening or if new symptoms arise, do not hesitate to seek medical attention sooner than the scheduled follow-up.

In summary, while it is natural to feel concerned about an enlarged lymph node, especially with the accompanying symptoms you have described, the current medical assessments suggest that it is likely benign. Regular follow-up and monitoring are appropriate next steps, and open communication with your healthcare provider will help address your concerns and ensure that any necessary interventions are made in a timely manner.

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