Managing PCOS: Concerns About Medication and Supplements - Obstetrics and Gynecology

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Issues Related to the Use of Polycystic Ovary Syndrome Medications


Hello Doctor: I previously asked you some questions about polycystic ovary syndrome (PCOS).
I have been diagnosed with PCOS, and you prescribed me Metformin to take for a month, one tablet a day.
I would like to know if I need to avoid taking other dietary supplements while on this medication.
I usually take calcium supplements, multivitamins, vitamin C, and B vitamins, so I want to know if these supplements will interact with Metformin or if there are any concerns.
Additionally, I have noticed that after taking Metformin, I experience noticeable side effects such as diarrhea and weakness in my limbs.
Is it appropriate to take this medication before bedtime? Will taking it at night lower my blood sugar and potentially lead to fainting or other dangers while I sleep? Thank you for your patience in reviewing and answering my questions.
Thank you!

Nickname, 20~29 year old female. Ask Date: 2013/04/11

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it is generally recommended to take Mylex with food to minimize the side effects of diarrhea and weakness in the limbs.
Therefore, you may discuss the timing of the medication with your physician.
Using it alongside dietary supplements should not have any adverse effects.
The medical information provided above is only a general guideline; the diagnosis and treatment of a patient's condition should be based on an in-person consultation with the attending physician.
Wishing you good health.
Sincerely, Dr.
Tsao Kuo-Tao, Director of the Department of Obstetrics and Gynecology, Taipei Hospital, Ministry of Health and Welfare.

Reply Date: 2013/04/11

More Info


Managing Polycystic Ovary Syndrome (PCOS) can be a complex process, especially when it comes to medication and dietary supplements. It’s great that you are seeking clarity on how to manage your condition effectively while considering the medications prescribed to you.


Understanding Your Medication: Metformin
From your previous messages, it appears that you have been prescribed Metformin, which is commonly used to improve insulin sensitivity in women with PCOS. This medication can help regulate menstrual cycles and may assist in weight management. However, it is important to note that Metformin can have gastrointestinal side effects, such as diarrhea and abdominal discomfort, especially when you first start taking it. These side effects often improve over time as your body adjusts to the medication.


Concerns About Supplements
Regarding your inquiry about taking supplements such as calcium, multivitamins, vitamin C, and B vitamins alongside Metformin, there are generally no significant interactions between these supplements and Metformin. However, it is always wise to consult with your healthcare provider about any supplements you are taking. Some vitamins and minerals can affect the absorption of medications, although this is not typically a concern with the ones you mentioned.


Timing of Medication
You mentioned taking Metformin at night and expressed concerns about potential hypoglycemia (low blood sugar) during sleep. Metformin is usually taken with meals to minimize gastrointestinal side effects and to help manage blood sugar levels effectively. Taking it at night is not inherently dangerous, but it is crucial to ensure that you are eating a balanced meal that includes carbohydrates to prevent any risk of hypoglycemia. If you are experiencing significant side effects like diarrhea or weakness, it may be worth discussing with your doctor whether the timing or dosage of your medication should be adjusted.


Monitoring Your Symptoms
If you are experiencing persistent side effects, such as diarrhea and weakness, it is essential to communicate this with your healthcare provider. They may consider adjusting your dosage or switching you to a different medication. It’s also important to monitor your blood sugar levels, especially if you have concerns about hypoglycemia. While Metformin is not typically associated with causing low blood sugar, it can occur, particularly if you are not eating adequately.


Lifestyle Considerations
In addition to medication, managing PCOS often involves lifestyle changes, including diet and exercise. A balanced diet that is low in refined carbohydrates and sugars can help manage insulin levels and improve symptoms. Regular physical activity is also beneficial for weight management and can help regulate menstrual cycles.


Conclusion
In summary, while there are generally no significant interactions between Metformin and the supplements you are taking, it is crucial to monitor your body’s response to the medication and communicate any side effects to your healthcare provider. They can provide personalized advice based on your specific situation. Always ensure that you are eating adequately when taking Metformin, especially if you choose to take it at night. Managing PCOS is a multifaceted approach that includes medication, lifestyle changes, and regular monitoring of your health. If you have any further questions or concerns, don’t hesitate to reach out to your healthcare provider for guidance.

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