Managing Atopic Dermatitis in Infants: Steroid vs. Non-Steroid Treatments - Pharmacology

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Skin Clean Ointment is a combination of corticosteroid ointments?


Hello Doctor: My child is currently six months old and has seen several doctors for atopic dermatitis.
Each doctor has provided different prescriptions and treatment approaches.
Most have prescribed steroid ointments, which have helped, but the rashes on the face reappear shortly after.
Yesterday, I consulted another doctor who prescribed a non-steroidal ointment, Hydrocortisone.
Previously, we have used other medications such as Eucerin, Cetaphil, and Topical corticosteroids, which were prescribed by the later doctor for different areas.
The most itchy areas for my baby are the scalp hairline, around the mouth, eyelids, and eyebrows, where rashes have appeared, and there are several scratches.
I am considering reintroducing a steroid medication.
I have read some information stating that steroids should not be applied to open wounds.
My questions are: Should I start with the Hydrocortisone ointment first? (Previous doctors said it was fine to use the steroid ointments they prescribed.) How long should I wait before starting the steroid ointments? Can I apply both ointments on the face while avoiding the wounds? Are these ointments safe to use around the eyelids and mouth? (I am also concerned about my baby ingesting them.) Currently, the red and swollen areas on my baby's face are starting to peel, and there are small rashes almost all over the face.
If I apply the ointment, it will cover the entire face; could this be problematic? I know steroids have side effects, so will the Hydrocortisone lead to resistance? I believe each doctor’s prescribed medication has its purpose, and I hope to find the best method to minimize the use of steroid ointments.
What would be the best way to combine these treatments? Thank you for your response, Doctor!

Xiao Ping, 30~39 year old female. Ask Date: 2013/05/08

Dr. Chen Shuzi reply Pharmacology


Hello! The topical use of corticosteroid ointments is currently the standard treatment for atopic dermatitis.
Corticosteroid ointments are typically used temporarily during acute flare-ups when rashes appear, and they should be discontinued once the inflammation subsides.
Their benefit lies in their ability to quickly and effectively suppress the inflammatory symptoms of the skin.
The strength classification of the ointments previously used for the baby is as follows: Hydrocortisone (weak), Fluticasone (medium), and Betamethasone dipropionate (strong).

In general, strong corticosteroids should be avoided on the face; it is recommended to use weak corticosteroid ointments on the facial area (avoiding the eyes and mouth).
When applying, it is important to use the corticosteroid ointment only on the inflamed areas of the skin and not on normal skin.
Normal-looking skin without inflammation should be treated with a moisturizer.

As for the recently used Fucidin Cream 5gm/tube, this is an antibiotic ointment that should only be used when there is an infection in the wound.
The above information is for your reference only! Please remember that the physician will prescribe medication based on the baby's clinical condition, so please use the medication according to the physician's prescription.
Wishing you peace and joy!

Reply Date: 2013/05/08

More Info


Managing atopic dermatitis (AD) in infants can be quite challenging, especially given the varying opinions and treatment approaches from different healthcare providers. At six months old, your child is at a stage where skin conditions like AD can be particularly troublesome, and it’s understandable to seek clarity on the best treatment options.


Steroid vs. Non-Steroid Treatments
1. Topical Corticosteroids: These are commonly prescribed for managing atopic dermatitis due to their anti-inflammatory properties. They can effectively reduce redness, itching, and inflammation. However, concerns about potential side effects, especially with long-term use, are valid. Side effects can include skin thinning, stretch marks, and in some cases, rebound flares when the medication is discontinued. For infants, it is crucial to use the lowest effective potency and for the shortest duration necessary to control symptoms.
2. Non-Steroidal Treatments: Medications like topical calcineurin inhibitors (e.g., Elidel or Protopic) are alternatives that do not carry the same risks as steroids. They are effective in managing inflammation and are generally safe for long-term use. However, they may not be as immediately effective as steroids in severe flare-ups.


Managing Your Child’s Condition
Given your child’s symptoms, including redness, itching, and the presence of scabs from scratching, it is essential to approach treatment carefully:
- Initial Treatment: If the skin is broken or has open wounds, it is generally advisable to avoid applying topical steroids directly on those areas until they have healed. Instead, you can start with a non-steroidal treatment like the one your recent doctor prescribed (膚即淨軟膏). This can help soothe the skin and reduce inflammation without the risks associated with steroids.

- Combination Use: Once the skin has improved and any open wounds have healed, you can consider using both types of treatments. For example, you might apply the non-steroidal ointment on less affected areas and the steroid ointment on areas with significant inflammation, but always avoid applying steroids on broken skin.

- Application Techniques: When applying any topical treatment, ensure that the skin is clean and dry. Apply a thin layer of the medication and gently rub it in. For sensitive areas like the face, including around the eyes and mouth, be cautious and consult your pediatrician or dermatologist about the safety of specific products in these regions.


Monitoring and Adjusting Treatment
- Watch for Side Effects: While using topical steroids, monitor for any signs of adverse effects, such as increased redness or irritation. If you notice these, consult your healthcare provider for alternative options.

- Hydration and Moisturization: Regularly applying a good moisturizer can help maintain skin hydration and barrier function, which is crucial in managing atopic dermatitis. Look for fragrance-free and hypoallergenic products.

- Avoid Triggers: Identify and minimize exposure to known triggers, such as certain fabrics, soaps, or allergens that may exacerbate your child’s condition.


Conclusion
In summary, managing atopic dermatitis in infants requires a balanced approach that considers both the benefits and risks of treatments. It is essential to work closely with your healthcare provider to tailor a treatment plan that addresses your child’s specific needs while minimizing potential side effects. Regular follow-ups can help adjust the treatment as necessary, ensuring your child remains comfortable and their skin healthy. If you have ongoing concerns or if the condition worsens, don’t hesitate to seek further medical advice.

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