Acne treatment
1.
Is isotretinoin suitable for treating severe (widespread) pustular acne in a 14-year-old adolescent? If so, is liver function testing necessary before starting the medication? Are there any long-term side effects associated with its use? (The doctor has currently prescribed a week of oral antibiotics and anti-inflammatory injections.)
2.
Additionally, the doctor intends to use birth control pills to help regulate hormones in the 14-year-old to assist in acne resolution.
Is this approach appropriate? Thank you!
SmileW, 40~49 year old female. Ask Date: 2013/08/22
Dr. Wu Yuxin reply Dermatology
1.
Severe cystic acne can be treated with oral isotretinoin, and it is necessary to monitor lipid levels and liver function tests.
Side effects vary among individuals, but the most common ones are elevated lipid levels and liver function tests.
2.
Birth control pills are primarily used to regulate endocrine function in women, but it is advisable to have an examination and recommendation from a gynecologist for safety.
Reply Date: 2013/08/22
More Info
When it comes to treating severe acne, particularly in teenagers, there are several effective options available, including A-retinoids (like isotretinoin) and hormonal therapies. Let's break down your questions regarding these treatments.
1. A-Retinoids for Severe Acne: A-retinoids, particularly isotretinoin, are often prescribed for severe, cystic acne that has not responded to other treatments. Isotretinoin is a powerful medication that can significantly reduce the size and activity of sebaceous glands, leading to a decrease in acne lesions. It is generally considered suitable for teenagers, including those as young as 14, but it must be prescribed and monitored by a healthcare professional due to its potential side effects.
Before starting isotretinoin, it is essential to conduct baseline liver function tests and lipid profiles. This is because isotretinoin can affect liver function and lipid levels, leading to elevated liver enzymes and triglycerides. Regular monitoring is also necessary throughout the treatment to ensure that these levels remain within a safe range.
Long-term use of isotretinoin can lead to several side effects, including dry skin, chapped lips, and potential mood changes. More serious risks include teratogenic effects (birth defects if taken during pregnancy), so it is crucial for female patients to use effective contraception during treatment and for a period after stopping the medication.
2. Hormonal Therapy for Acne: Hormonal therapies, such as oral contraceptives, can be effective in treating acne in females by regulating hormones that contribute to acne development. These medications can help reduce sebum production and improve skin condition. For a 14-year-old, the use of hormonal therapy should be carefully considered and discussed with a healthcare provider.
The appropriateness of prescribing birth control pills for acne management in a teenager depends on several factors, including the severity of the acne, the patient's overall health, and whether they are sexually active. It is also important to discuss the potential side effects of hormonal therapy, which can include weight gain, mood changes, and an increased risk of blood clots.
In summary, both A-retinoids and hormonal therapies can be effective treatments for severe acne in teenagers. However, they require careful consideration and monitoring by a healthcare professional. If your doctor has prescribed antibiotics and anti-inflammatory injections as an initial treatment, this is a common approach to manage acne while considering more long-term solutions like isotretinoin or hormonal therapy.
It is essential to maintain open communication with your healthcare provider about any concerns regarding side effects or the effectiveness of the treatment plan. Regular follow-ups will help tailor the treatment to your specific needs and ensure the best possible outcome for managing acne.
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