History of nasopharyngeal carcinoma, X-ray of the neck shows white spots, slight hemoptysis?
Hello Doctor: My mother was diagnosed with nasopharyngeal cancer two years ago.
After more than six months of chemotherapy and radiation therapy, she now has regular follow-up appointments every month.
Recently, when she cleans her nasal passages in the morning, she occasionally experiences coughing up blood.
Although it is only a small amount of fresh blood each time, she mentioned this to her attending physician during her follow-up visit, after which she underwent an X-ray and blood tests.
During her next visit, the X-ray showed some white spots in the neck area.
The attending physician suggested performing an invasive vascular examination or a CT scan along with a sputum culture.
What could be the possible causes of this? My mother does not have any phlegm; she only coughs up secretions from post-nasal drip.
Can a bacterial culture still be performed in this case? Thank you for your assistance! Best regards, NIL.
NIL, 30~39 year old female. Ask Date: 2013/09/06
Dr. Zheng Jueyi reply Otolaryngology
Hello, based on your description, my main concern is the possibility of nasopharyngeal cancer recurrence or lung metastasis, which could be causing the bleeding.
I recommend coordinating with your physician for relevant examinations to determine whether the bleeding is due to the tumor or simply a result of the mucosal fragility following radiation therapy.
Regarding bacterial cultures, as long as there are secretions, cultures can still be performed.
Wishing you safety and good health.
Sincerely, Dr.
Jue-Yi Cheng, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.
Reply Date: 2013/09/06
More Info
Understanding the situation regarding your mother's nasopharyngeal cancer and the recent symptoms she is experiencing is crucial for her ongoing care. Given her history of cancer and the current symptoms of coughing up blood, it is essential to approach this matter with careful consideration of potential causes and necessary diagnostic steps.
Possible Causes of Coughing Blood
1. Post-Nasal Drip: Since you mentioned that your mother is coughing up blood mixed with nasal secretions, one likely cause could be post-nasal drip. This occurs when excess mucus accumulates in the back of the throat, often leading to irritation and coughing. If the nasal passages are inflamed or irritated, it can result in minor bleeding.
2. Radiation Effects: After radiation therapy for nasopharyngeal cancer, the tissues in the throat and nasal cavity can become sensitive and fragile. This fragility can lead to bleeding, especially if there is any irritation from coughing or nasal cleaning.
3. Infection: Another possibility is an infection, such as sinusitis or bronchitis, which can cause inflammation and bleeding. Given her history of cancer, any new infection should be taken seriously.
4. Tumor Recurrence: Although less likely, it is essential to consider the possibility of tumor recurrence or new lesions in the nasopharyngeal area or surrounding tissues. This is particularly relevant given her history of cancer.
5. Vascular Issues: Sometimes, the blood vessels in the nasal cavity can become engorged or fragile, leading to bleeding. This can happen due to various reasons, including inflammation or irritation from treatment.
Diagnostic Steps
The recommendation from her physician to conduct further imaging and possibly invasive procedures is prudent. Here’s a breakdown of the suggested steps:
1. X-ray Findings: The appearance of white spots in the neck area on the X-ray could indicate several things, including lymphadenopathy (enlarged lymph nodes), which can be a sign of infection or recurrence of cancer. Further imaging, such as a CT scan, can provide more detailed information.
2. Invasive Vascular Examination: This may be suggested to assess any vascular abnormalities that could be contributing to the bleeding. It is essential to evaluate the blood vessels in the area for any signs of abnormality.
3. Sputum Culture: While your mother may not have significant sputum production, it is still possible to collect samples from the back of the throat or nasal secretions for culture. This can help identify any bacterial infections that may be present.
Importance of Follow-Up
Given your mother's history of nasopharyngeal cancer, it is crucial to maintain regular follow-ups with her oncologist and ENT specialist. Any new symptoms, especially those involving bleeding, should be reported immediately. The healthcare team will consider her entire clinical picture, including her cancer history, current symptoms, and diagnostic findings, to determine the best course of action.
Conclusion
In summary, the coughing up of blood, especially in a patient with a history of nasopharyngeal cancer, warrants thorough investigation. The potential causes range from benign issues like post-nasal drip to more serious concerns such as tumor recurrence. It is essential to follow through with the recommended diagnostic tests and maintain open communication with her healthcare providers. Early detection and intervention are key in managing her health effectively. Please ensure that your mother attends all follow-up appointments and discusses any new or worsening symptoms with her doctors.
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