Antibiotic Use for Urinary Tract Infections: Common Questions - Urology

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Urinary tract infections and medication issues?


The patient has been experiencing frequent urination, a burning sensation, strong-smelling urine, dull lower back pain, and a feeling of slight fever without actual fever for the past week.
They underwent urine tests and lumbar X-rays, both of which returned normal results.
The physician prescribed antibiotics: doxycycline capsules, Lurbinectedin, and Debridat.
The patient is inquiring why antibiotics were prescribed despite normal urine tests and whether such a condition warrants antibiotic treatment.
They also want to know if it is possible to have an infection despite normal urine tests.
Additionally, they are asking about the differences between Doxycycline, Lurbinectedin, and Debridat, noting that Doxycycline is often used in dermatology.
Thank you.

Afa, 30~39 year old female. Ask Date: 2013/10/14

Dr. Xu Weikai reply Urology


Hello, it is recommended to perform an ultrasound examination of the kidneys.
Not all urinary tract infections can cause abnormalities in urine.
A urine culture can be conducted to identify the specific bacteria, and appropriate medications can be prescribed based on the type of bacteria.
Zosyn, Levofloxacin, and Doxycycline capsules are all antibiotics, but they have different mechanisms of action.
Note: Zosyn and Levofloxacin should contain the same active ingredients.
If there are any unclear points, feel free to ask again for further discussion and research.
Online responses should only be used as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
Ministry of Health and Welfare, Taitung Hospital, cares about you.

Reply Date: 2013/10/14

More Info


When it comes to urinary tract infections (UTIs), understanding the appropriate use of antibiotics is crucial for effective treatment and prevention. Your symptoms of frequent urination, burning sensation, strong-smelling urine, and dull lower back pain suggest a possible UTI, even if your urine tests came back normal. It's important to note that urine cultures can sometimes yield negative results despite the presence of an infection, particularly if the bacteria are present in low numbers or if the sample was not collected properly.
Antibiotics are often prescribed based on clinical judgment, especially when a physician suspects an infection based on symptoms, even if lab results are inconclusive. In your case, the doctor may have decided that the symptoms you are experiencing warrant a trial of antibiotics to see if they alleviate your discomfort. This approach is common in clinical practice, especially when the risk of untreated infection is considered.

Regarding the antibiotics you mentioned—Doxycycline, Loperamide, and another medication (likely a proton pump inhibitor or similar)—each serves different purposes. Doxycycline is a broad-spectrum antibiotic that can treat various bacterial infections, including some UTIs. Loperamide is typically used to manage diarrhea, and it seems there might be a misunderstanding regarding its use in your treatment. If you were prescribed a medication for gastrointestinal issues, it may not be directly related to your UTI treatment.

As for the other medications you mentioned, such as probiotics (like "Zojing" and "Lezuoxin"), these are often used to help restore the natural flora of the gut and may aid in recovery after antibiotic treatment. They do not directly treat UTIs but can be beneficial in maintaining overall gut health, especially after a course of antibiotics.

If you are experiencing persistent symptoms despite antibiotic treatment, or if new symptoms arise, it is essential to follow up with your healthcare provider. They may consider further testing, such as imaging studies or a repeat urine culture, to rule out other potential issues, such as kidney stones or other underlying conditions.

In terms of prevention, there are several strategies you can adopt to reduce the risk of recurrent UTIs. These include:
1. Hydration: Drink plenty of fluids, especially water, to help flush out bacteria from your urinary tract.

2. Hygiene: Maintain good personal hygiene, particularly after sexual activity, to minimize the risk of introducing bacteria into the urinary tract.

3. Urination Habits: Urinate when you feel the urge and do not hold it in for extended periods. After sexual intercourse, urinating can help clear any bacteria that may have entered the urethra.

4. Cranberry Products: Some studies suggest that cranberry juice or supplements may help prevent UTIs, although the evidence is mixed.

5. Probiotics: Consider taking probiotics, as they may help maintain a healthy balance of bacteria in the urinary tract.

In conclusion, while your urine tests may have returned normal results, the clinical presentation of your symptoms led your physician to prescribe antibiotics as a precautionary measure. If symptoms persist or worsen, further evaluation is warranted. Always communicate openly with your healthcare provider about your symptoms and any concerns you may have regarding your treatment.

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