Managing Acne with Diane-35: Dosage Guidance for Irregular Periods

Taking Diane-35

Hello Doctor: Due to my acne issues, I took Cibion Tab 50mg and Vanmycin for the first month, which improved the inflammation somewhat, but did not resolve the problem with milia.
Therefore, after one month, the doctor suggested I take Diane-35.
However, my menstrual cycle occurs every three months, but it is very regular (a few years ago, I consulted a doctor who said no special treatment was needed, so I have not paid much attention to it).
I would like to know if I should follow the method of taking it for three weeks and then stopping for one week, or should I take it for three months and only stop when my period comes? Because during the stopping period (not during my period), my condition worsens.

Mei, 20~29 year old female. Ask Date: 2001/07/01

Dr. Wei Fumao reply Obstetrics and Gynecology

It is still advisable to take a break from medication.
If a seven-day cessation is too long, consider stopping the medication for four days before resuming the next dose.
If there has been sexual activity, it is important to be aware of potential pregnancy and contraception issues.

Reply Date: 2001/07/01

More Info

When managing acne with Diane-35, especially in the context of irregular menstrual cycles, it's essential to understand both the medication's mechanism and the appropriate dosing schedule. Diane-35 is a combination oral contraceptive that contains cyproterone acetate and ethinyl estradiol. It is often prescribed not only for contraception but also for treating acne due to its anti-androgenic properties, which help reduce sebum production and improve skin conditions.

Given your situation, where you experience a menstrual cycle every three months, it is crucial to follow the recommended dosing schedule for Diane-35. Typically, the standard regimen involves taking the pill for 21 consecutive days followed by a 7-day break. However, in your case, since you have a very irregular cycle, you might consider a modified approach.
1. Continuous Use: Since you mentioned that your acne worsens during the off-period, you may benefit from taking Diane-35 continuously without the 7-day break. This means you would take the pill for three months straight and then take a break only if necessary. Continuous use can help maintain stable hormone levels, which may prevent the flare-ups of acne that occur during the off-period.

2. Monitoring Symptoms: It's important to monitor your symptoms closely. If you notice significant side effects or if your acne does not improve, you should consult your healthcare provider. They may suggest adjusting the dosage or switching to a different medication that might be more suitable for your specific condition.

3. Consultation with Healthcare Provider: Always keep an open line of communication with your healthcare provider. They can provide personalized advice based on your medical history and current health status. If you experience side effects such as breast tenderness or mood changes, these should be discussed with your doctor, as they may indicate the need for a dosage adjustment or a change in medication.

4. Consideration of Other Factors: Remember that acne can be influenced by various factors, including diet, stress, and skincare routines. Alongside medication, consider adopting a holistic approach that includes a balanced diet, proper hydration, and a skincare regimen tailored to acne-prone skin.

5. Long-term Use and Breaks: If you are on Diane-35 for an extended period, it is generally recommended to take breaks periodically to assess your skin condition and overall health. However, this should be done under medical supervision. Your doctor may recommend a break after a certain period of continuous use, such as after three months, to evaluate the effectiveness of the treatment and any potential side effects.

In summary, while the standard regimen for Diane-35 involves a 21-day on and 7-day off cycle, your unique situation with irregular periods may warrant a continuous approach. Always consult with your healthcare provider to tailor the treatment plan to your specific needs and to ensure that you are managing both your acne and any potential side effects effectively.

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