Optic Nerve Atrophy: Causes, Symptoms, and Treatment Options - Ophthalmology

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About optic nerve atrophy?


Due to a car accident in April of last year, I suffered from intracranial hemorrhage in my right hemisphere.
At the time of the accident, it was uncertain whether my right eye was impacted.
After undergoing brain surgery, I was in a coma for about one to two weeks.
When I regained consciousness, I noticed that my vision in the right eye was strange; I experienced double vision when looking at things, and my pre-existing myopia seemed to have worsened.
Wearing my original glasses made me dizzy and unable to see clearly.
Later, my family mentioned that my right eye appeared to be deviating outward.
After an examination by a doctor, it was found that I had developed exotropia in my right eye.
Further examination at an ophthalmology hospital revealed that my right optic nerve had atrophied.
I would like to ask the doctor several questions:
1.
Can optic nerve atrophy cause strabismus?
2.
Will optic nerve atrophy worsen over time and lead to blindness?
3.
If only the right optic nerve is atrophied, will the left optic nerve also atrophy as a consequence?
4.
With the presence of optic nerve atrophy and exotropia, can strabismus surgery help address my double vision problem?
5.
It has been almost a year since the accident, and I feel my right eye has improved slightly.
Although I still see double, things seem clearer than before.
Does this indicate that my optic nerve is improving, or have I simply adapted to using my left eye, leading to a misjudgment?
6.
I often cover my left eye and use my right eye with optic nerve atrophy for tasks or writing.
Does this help in the recovery of my right optic nerve, or could it worsen the condition?
7.
If my glasses prescription is insufficient due to optic nerve atrophy, will this exacerbate the atrophy or worsen my myopia?
8.
What treatments are available for optic nerve atrophy? Currently, I am following the recommendations of my neurosurgeon to take neuroprotective agents and a B-complex vitamin supplement to manage these sequelae.
Are there any other methods to treat optic nerve atrophy? Is there really no chance for improvement? I am still young, and the road ahead is long; I feel very distressed and am living in pain.

Wan Nian Ju Hui, 20~29 year old female. Ask Date: 2014/03/31

Dr. Gao Pilin reply Ophthalmology


Hello: Optic nerve atrophy itself does not cause strabismus; it is possible that the extraocular muscles are also affected, or that the eyes may deviate due to impaired vision.
If optic nerve atrophy becomes more severe, it can lead to blindness.
If only the right eye has optic nerve atrophy and the left eye was not injured at that time or afterward, the left eye should not also experience optic nerve atrophy.
If optic nerve atrophy is accompanied by exotropia, strabismus surgery can be performed to address cosmetic concerns, but the issue of double vision may not be completely resolved.
Regarding double vision, our brain tends to suppress the image from the right eye, which helps reduce interference between the two eyes.
Optic nerve atrophy is fundamentally an irreversible condition; covering the left eye and using the right eye with optic nerve atrophy for tasks or writing is unlikely to benefit the recovery of the right optic nerve.
Following the advice of a neurosurgeon to take routine medications like neurotropic agents and B-complex vitamins may help delay symptoms, but it cannot treat or cure the condition.
Life is still long ahead; protecting the left eye should allow for a normal life, so please do not be discouraged.
For eye issues, it is advisable to visit a medical center or teaching hospital's neuro-ophthalmology department for a thorough examination.
It is best to have a neuro-ophthalmologist provide accurate answers based on the examination results.
Thank you for your letter.

Reply Date: 2014/03/31

More Info


Optic nerve atrophy is a condition characterized by the degeneration of the optic nerve, which can lead to various visual impairments. Given your history of a traumatic brain injury from a car accident, it's understandable that you're experiencing significant concerns regarding your vision and overall eye health. Let's delve into your questions regarding optic nerve atrophy, its causes, symptoms, and treatment options.


Causes of Optic Nerve Atrophy
Optic nerve atrophy can result from several factors, including trauma, as in your case, where intracranial hemorrhage may have affected the optic nerve's function. Other potential causes include:
1. Ischemia: Reduced blood flow to the optic nerve can lead to atrophy.

2. Infections: Conditions like optic neuritis or other infections can damage the nerve.

3. Toxins: Exposure to certain toxins or drugs can lead to nerve damage.

4. Genetic Disorders: Some hereditary conditions can predispose individuals to optic nerve atrophy.


Symptoms of Optic Nerve Atrophy
The symptoms you are experiencing, such as double vision (diplopia) and changes in visual acuity, are common in individuals with optic nerve atrophy. Other symptoms may include:
- Loss of peripheral vision
- Difficulty with color vision
- Visual field defects

Relationship Between Optic Nerve Atrophy and Strabismus
To address your question about whether optic nerve atrophy can cause strabismus (misalignment of the eyes), the answer is yes. Damage to the optic nerve can disrupt the coordination between the eyes, leading to misalignment. This misalignment can further exacerbate visual disturbances, such as double vision.


Progression of Optic Nerve Atrophy
Regarding the progression of optic nerve atrophy, it can vary from person to person. In some cases, the atrophy may stabilize, while in others, it may worsen over time, potentially leading to significant vision loss. The fact that you have noticed some improvement in your right eye's clarity could indicate a degree of recovery, but it's essential to have realistic expectations. The brain's ability to adapt to changes in vision can sometimes create the illusion of improvement.


Treatment Options
Currently, there is no definitive treatment to reverse optic nerve atrophy. However, several approaches may help manage symptoms and improve quality of life:
1. Vision Rehabilitation: Working with a vision therapist can help you adapt to changes in your vision and improve your functional abilities.

2. Corrective Lenses: While you mentioned that your glasses may not be helping, it's crucial to have an accurate prescription. Poorly fitted glasses can exacerbate visual issues.

3. Nutritional Support: Continuing with vitamin B supplementation, as suggested by your doctor, may support nerve health. Some studies suggest that antioxidants and omega-3 fatty acids may also be beneficial.

4. Surgical Options: Strabismus surgery may help align your eyes, potentially reducing double vision. However, the success of such surgery depends on the underlying cause and the degree of nerve damage.


Self-Care and Management
Using your left eye to compensate for the right eye's vision may help you adapt, but it's essential to avoid overstraining the affected eye. Engaging in activities that promote visual skills and coordination can be beneficial, but always consult with your healthcare provider before starting any new regimen.


Conclusion
In summary, optic nerve atrophy can lead to various visual disturbances, including strabismus and double vision. While there is no cure, management strategies can help improve your quality of life. Regular follow-ups with your ophthalmologist and neurologist are crucial to monitor your condition and adjust your treatment plan as needed. Remember, it's essential to maintain open communication with your healthcare providers about your symptoms and any changes you experience. Your concerns are valid, and seeking support from professionals can help you navigate this challenging situation.

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