Gonorrhea: Symptoms, Diagnosis, and Treatment Options - Internal Medicine

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About Gonorrhea


Hello Doctor, I accidentally encountered a risky situation before, and afterwards I experienced painful urination.
The pain during urination has resolved, but I have been experiencing persistent pain in my inner thigh and groin area for two months, and I have not been able to find the cause.
I have tested negative for gonorrhea, chlamydia, and HIV and syphilis after 90 days.
I have seen many doctors and taken tetracycline and ciprofloxacin without any improvement.
My lymph nodes are not swollen.
Recently, I visited an infectious disease specialist who said he could treat me for gonorrhea, but he felt my symptoms were not typical because I only have a small amount of clear white discharge.
He mentioned that gonorrhea typically presents with yellow discharge.
However, he administered an injection of gonorrhea treatment, and I felt significantly better in my inner thigh and groin area; the pain has gradually decreased.
Does this mean I have gonorrhea? Or could it be that the injection treated another infection? I have had over five urine cultures for gonorrhea, and generally, my urine bacterial cultures have been normal.
Can gonorrhea be detected through urine tests? I am very concerned about transmitting anything to my partner.
Is there any need for follow-up? Do I need to continue taking medication? Thank you for your response, Doctor.

A-Jie, 20~29 year old female. Ask Date: 2014/04/05

Dr. Liao Zhongxin reply Internal Medicine


Dear readers,
1.
First, let’s introduce gonorrhea based on information from the Centers for Disease Control:
(A) Transmission: The primary mode of transmission for gonorrhea is through sexual intercourse.
It can also be transmitted if an open wound comes into direct contact with an infected person's semen, blood, vaginal secretions, or other mucosal fluids.
Infants can contract the infection during delivery if the mother has gonorrhea, leading to conjunctivitis in newborns.

(B) Incubation period: The typical incubation period for gonorrhea is about 2 to 3 days, but it can be longer.

(C) Symptoms: Clinical symptoms differ between genders.
In men, symptoms typically appear 2 to 7 days after infection and may include: purulent urethral discharge, painful or burning sensation during urination.
Some patients may resolve the infection on their own, while others may become asymptomatic carriers.
However, the Neisseria gonorrhoeae bacteria can still enter the body through the urethra, potentially causing systemic symptoms, and may lead to inflammation of the seminal vesicles and prostate, infertility, and urethral stricture.
Additionally, men who have sex with men often experience rectal infections, which may present with itching and discharge, but most have no obvious symptoms.
In women, symptoms may appear a few days after infection, including urethritis or cervicitis, often without pain and may be subtle, leading to neglect.
Women are also prone to bladder infections due to gonorrhea, presenting with frequent urination and burning sensations.
About 20% of women may develop uterine infections due to their menstrual cycle, leading to endometritis, salpingitis, or pelvic inflammatory disease, which can ultimately result in ectopic pregnancy or infertility.
Furthermore, newborns can easily contract gonococcal conjunctivitis during delivery if the mother is infected, which, if not properly treated, may lead to blindness.

(D) Prevention methods: 1.
Avoid multiple sexual partners.
2.
Use condoms consistently and correctly during sexual activity; if lubrication is needed, use water-based lubricants and avoid oil-based substances (like baby oil or petroleum jelly) to prevent condom breakage.
3.
If you suspect you have gonorrhea, do not self-medicate or rely on folk remedies; seek medical attention promptly for early diagnosis and treatment.
4.
If a mother is infected with untreated gonorrhea, she should inform her physician, who can administer antibiotic eye drops to the newborn at birth to effectively prevent gonococcal infection.

Treatment methods and medical information: There are currently antibiotics available that can effectively treat gonorrhea.
If you exhibit clinical symptoms of gonorrhea or suspect you are infected, seek medical treatment immediately.
You can visit urology, dermatology, or obstetrics and gynecology departments in medical facilities, or refer to the list of recommended sexually transmitted disease clinics provided by the health department, and also get tested for HIV.

2.
From the above, it is clear that gonorrhea is transmitted through sexual activity, with differing presentations in men and women; moreover, Neisseria gonorrhoeae is difficult to culture.
A simple method for diagnosis is to take a sample from the affected area for a Gram stain; if pink-stained diplococci are present within the cells, a diagnosis can be confirmed for treatment.

3.
After treatment, if there are any further issues, please follow up at a hospital or clinic to avoid misinformation.
Thank you!

Reply Date: 2014/04/05

More Info


Gonorrhea, caused by the bacterium Neisseria gonorrhoeae, is a sexually transmitted infection (STI) that can affect various parts of the body, including the genitals, rectum, and throat. Understanding the symptoms, diagnosis, and treatment options for gonorrhea is crucial, especially in your case where you have experienced persistent pain in the groin area.


Symptoms of Gonorrhea
Common symptoms of gonorrhea in men include:
- Painful urination (dysuria)
- Pus-like discharge from the penis, which can be yellow or white
- Swollen or painful testicles
- Pain in the groin area
In women, symptoms may be less noticeable and can include:
- Increased vaginal discharge
- Painful urination
- Abdominal or pelvic pain
- Bleeding between periods
Given that you experienced painful urination initially, it is possible that you had a gonorrhea infection. However, the absence of a yellow discharge and the negative results from multiple tests raise questions about the diagnosis.


Diagnosis
Diagnosis of gonorrhea typically involves:
- Urine tests: A urine sample can be tested for the presence of Neisseria gonorrhoeae.

- Swab tests: A healthcare provider may take a swab from the urethra, throat, or rectum, depending on the sexual practices.

- Cultures: In some cases, a culture may be performed to identify the bacteria.

It is important to note that while urine tests are commonly used, they may not always detect the infection, especially if the infection is localized or if the sample is not collected properly.


Treatment Options
The standard treatment for gonorrhea has evolved due to increasing antibiotic resistance. The Centers for Disease Control and Prevention (CDC) currently recommends a dual therapy approach:
1. Ceftriaxone: An injectable antibiotic.

2. Azithromycin: An oral antibiotic.

In your case, it seems that the injection you received was aimed at treating gonorrhea, which may explain the improvement in your symptoms. However, it is also possible that the injection had an effect on another underlying issue, such as a different bacterial infection or inflammation.


Follow-Up and Prevention
Given your history and the treatments you've undergone:
- Follow-Up Testing: It is advisable to have follow-up testing to confirm that the infection has been cleared. This may include repeat urine tests or swabs.

- Partner Notification: If you have been diagnosed with gonorrhea, it is essential to inform any sexual partners so they can also get tested and treated if necessary.

- Safe Practices: To prevent future infections, consider using condoms and engaging in safer sexual practices.


Conclusion
While your symptoms improved after the treatment, it is crucial to continue monitoring your health. If you have ongoing concerns or if symptoms return, seek further evaluation from a healthcare provider. They may recommend additional tests or treatments based on your specific situation. Remember, open communication with your healthcare provider about your symptoms and concerns is key to managing your health effectively.

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