Drug Allergies: Symptoms and Precautions for Patients

Q: Drug Allergies: Symptoms and Precautions for Patients

Dear： When it comes to drug allergies, healthcare professionals can only determine which medication caused the reaction based on the patient's allergy history and the likelihood of an allergic reaction to the medications taken at that time. <br>Naturally, all medications taken du

Drug allergy

Due to lymphadenitis in the neck, I visited an ENT specialist and after taking two packs of medication, I noticed red spots on my body while showering, which looked somewhat like mosquito bites but did not resemble hives.
Since I have a history of skin allergies, I didn't pay much attention to it.
The next day, after taking the fourth pack of medication, I experienced swelling in my neck and face, and my throat felt tight, making it a bit difficult to breathe.
On the third day, during a follow-up appointment, the doctor said it was an allergy to aspirin and advised that I should not take Tylenol in the future.
I would like to confirm if I am truly allergic to aspirin and Tylenol, as I have previously taken over-the-counter medications without any allergic reactions.
Below is the list of medications I took: 1.
AMOXICILLIN CAPSULE 2.
VORTAGEN E.M.
CAPSULES 3.
BROEN-C ENTERIC F.
4.
GACID TABLETS "H.H" 5.
LACTAM TABLETS (AC).
Please help me review this, thank you.

Miss Zhang, 20~29 year old female. Ask Date: 2014/05/12

Dr. Liao Lingmei reply Pharmacology

Dear: When it comes to drug allergies, healthcare professionals can only determine which medication caused the reaction based on the patient's allergy history and the likelihood of an allergic reaction to the medications taken at that time.
Naturally, all medications taken during that time could potentially be the culprits, and some doctors may even recommend that patients list all five medications as ones to avoid in the future.

The first medication, AMOXICILLIN, is an antibiotic.
If an allergic reaction occurs after taking it, common reactions include general skin reactions.
It is important to note that a small number of individuals may experience severe allergies to this medication, known as Penicillin allergy, which can lead to life-threatening anaphylactic shock.
Your symptoms align with a rash and some allergic reactions, but further testing is needed for a definitive diagnosis.
The second medication, VORTAGEN, contains Diclofenac.
Allergic reactions to this medication may present as skin rashes and angioedema, which can lead to small vessel swelling causing facial swelling or respiratory tract swelling that affects breathing.
This medication is classified as a non-steroidal anti-inflammatory drug (NSAID), and your doctor may suggest that you are allergic to aspirin based on this.
The third medication is an enzyme used to enhance anti-inflammatory and anti-edema effects, while the fourth medication is a gastric medication; the likelihood of these two causing an allergic reaction is low.
The fifth medication is acetaminophen (Tylenol).
If you have previously taken cold medications containing acetaminophen without any issues, the likelihood of an allergy to this medication is also low.

Aspirin and acetaminophen are not the same medications; the medications taken this time did not include aspirin but did contain acetaminophen.
You mentioned that you have previously taken over-the-counter medications without any allergic experiences.
The most accurate approach would be to list the ingredients of the over-the-counter medications you have taken in the past, which could help rule out the medications on the current list.
Otherwise, we can only make guesses and assumptions at this point.
I hope you find this response satisfactory.
Wishing you all the best for your health and happiness!
P.S.
I am a pharmacist...

Reply Date: 2014/05/12

More Info

Understanding drug allergies is crucial for patients, especially when experiencing symptoms that may indicate an adverse reaction to medications. In your case, it appears that you have developed symptoms after taking a series of medications, which raises concerns about potential drug allergies.

Symptoms of Drug Allergies
Drug allergies can manifest in various ways, and the symptoms you described—red, raised patches on your skin resembling hives, swelling in the neck and face, and a feeling of tightness in the throat—are indicative of an allergic reaction. Common symptoms of drug allergies include:
1. Skin Reactions: This can include rashes, hives (urticaria), or redness. These reactions can occur shortly after taking the medication or may develop after several doses.

2. Respiratory Symptoms: Difficulty breathing, wheezing, or a feeling of tightness in the throat can indicate a more severe allergic reaction, such as anaphylaxis, which requires immediate medical attention.

3. Swelling: Angioedema, or swelling of the deeper layers of the skin, particularly around the eyes and lips, can occur and may be accompanied by difficulty swallowing or breathing.

4. Gastrointestinal Symptoms: Nausea, vomiting, or diarrhea may also occur in some cases.

Precautions for Patients
Given your experience, here are some important precautions to consider:
1. Identify and Avoid Triggers: Since your doctor has indicated a possible allergy to aspirin (acetylsalicylic acid) and paracetamol (acetaminophen), it is essential to avoid these medications in the future. Always inform healthcare providers about your allergies before receiving any treatment.

2. Keep a Medication Diary: Document any medications you take, along with the dates and any symptoms experienced. This can help identify patterns and assist healthcare providers in managing your care.

3. Consult with an Allergist: If you suspect a drug allergy, consider seeing an allergist for further evaluation. They may conduct tests to confirm the allergy and provide guidance on safe medication alternatives.

4. Carry Emergency Medication: If you have a history of severe allergic reactions, your doctor may prescribe an epinephrine auto-injector (EpiPen) for emergency use in case of anaphylaxis.

5. Educate Yourself and Others: Make sure that you and those close to you understand your allergies. Wear a medical alert bracelet that indicates your allergies, which can be crucial in emergencies.

Regarding Your Current Medications
You mentioned taking several medications, including:
1. Amoxicillin: An antibiotic used to treat bacterial infections. Allergies to amoxicillin can also occur, leading to rashes or more severe reactions.

2. Vortagen E.M. (possibly an anti-inflammatory or analgesic): If this medication contains ingredients similar to aspirin, it may also pose a risk for those with aspirin allergies.

3. Broen-C Enteric F.: This may contain ingredients that could provoke an allergic reaction, depending on your sensitivities.

4. Gacid Tablets: If this is an antacid or similar medication, it is less likely to cause allergic reactions but should still be monitored.

5. Lactam Tablets: If these are beta-lactam antibiotics (like penicillin), they can also cause allergic reactions in some individuals.

Conclusion
It is essential to communicate openly with your healthcare provider about your symptoms and any concerns regarding drug allergies. Your experience with swelling and respiratory distress after taking medication is serious and warrants careful monitoring and management. Always prioritize your health and safety by being proactive about your allergies and seeking medical advice when needed.

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