Microscopic Hematuria, Glucose, and Protein in Urine - Internal Medicine

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Microscopic hematuria, glucose, and protein in the urine?


Dr.
Lee: Hello! I had a pre-employment physical examination on May 20, and on May 29, the report indicated that I had microscopic hematuria at 3+.
I went for another urinalysis on May 31, and today, June 6, I received the detailed report as follows:
Urinalysis:
- Appearance: Clear
- Color: Light yellow
- pH: 6.5
- Specific Gravity: 1.017
- Glucose: 1+
- Ketone: Negative
- Protein: Trace
- Blood: 2+
- Bilirubin: Negative
- Urobilinogen: No excess
- Nitrite: Negative
Microscopic Examination:
- WBC: 6 cells/uL; 1 cells/HPF
- RBC: 200 cells/uL; 36 cells/HPF
- Epithelial Cells: 9 cells/uL; 2 cells/HPF
- Casts: Nil
- Crystal: Nil
- Mucus: Nil
- Bacteria: Nil
- Yeast Cells: Nil
Doctor, am I suffering from kidney disease? Do I have diabetes? If I have diabetes and kidney disease, how serious is it? I am very worried because I had an appendectomy on January 30 of this year, and I also have polycystic ovary syndrome.
Could this have an impact? Additionally, I had a urinary catheter inserted after the appendectomy; could this be related to the hematuria? I would appreciate your response.
Thank you! Yu-Yan

Yu Yan, 30~39 year old female. Ask Date: 2014/06/06

Dr. Li Zhiyao reply Internal Medicine


Hello Yu-Yan: If your tests were not conducted during your menstrual period, based on the report results, there is indeed a need to suspect the possibility of kidney disease (urinary tract disorders) and diabetes.
However, further examinations are necessary; the diagnosis of diabetes should be based on blood glucose levels and glycated hemoglobin, while urine glucose is only for reference.
For the hematuria, it is recommended that you consult a urologist for further evaluation, as there are many causes that can lead to hematuria.
The likelihood that the hematuria is due to the catheterization performed over four months ago is low, so it is better to actively investigate the cause and seek early treatment.
Wishing you good health!

Reply Date: 2014/06/06

More Info


Understanding the presence of microscopic hematuria, glucose, and protein in urine is crucial for assessing kidney health and potential underlying conditions. Based on your urinalysis results, there are several key points to consider.

Firstly, the presence of microscopic hematuria (200 red blood cells per microliter) is significant and warrants further investigation. Hematuria can arise from various causes, including urinary tract infections, kidney stones, trauma, or more serious conditions such as glomerulonephritis or tumors. Given your recent history of appendectomy and urinary catheterization, it is less likely that these procedures directly caused the hematuria, but they could have contributed to irritation or infection in the urinary tract. It is essential to consult a urologist for a thorough evaluation, which may include imaging studies or cystoscopy to identify the source of bleeding.

Secondly, the presence of glucose in your urine (1+) suggests that your blood glucose levels may be elevated, which could indicate diabetes or impaired glucose tolerance. However, urine glucose is not a definitive diagnostic tool for diabetes; blood tests, including fasting blood glucose and HbA1c, are necessary for an accurate diagnosis. Your concern about diabetes is valid, especially if you have risk factors or symptoms associated with the condition. Maintaining blood glucose levels within a normal range is crucial to prevent complications, including kidney damage.

The trace amount of protein in your urine is also noteworthy. While it may not indicate significant kidney damage at this stage, persistent proteinuria can be a sign of kidney disease, particularly in the context of diabetes. Monitoring your kidney function through regular urine tests and blood tests (such as serum creatinine and estimated glomerular filtration rate) is essential. If protein levels increase, further evaluation may be required to assess for diabetic nephropathy or other renal conditions.

In terms of your overall health, having polycystic ovary syndrome (PCOS) and a history of abdominal surgery may complicate your situation. PCOS can be associated with insulin resistance, which increases the risk of developing type 2 diabetes. Therefore, lifestyle modifications, including a balanced diet and regular exercise, are vital in managing both PCOS and potential diabetes.

To summarize, your urinalysis results indicate the need for further evaluation of hematuria, potential diabetes, and proteinuria. It is crucial to follow up with healthcare professionals who can provide comprehensive assessments and management plans tailored to your specific needs. Early detection and intervention are key to preventing complications, particularly concerning kidney health. Regular monitoring, lifestyle changes, and adherence to medical advice will be essential in managing your health moving forward.

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