Chronic Throat Pain: Unraveling Persistent Symptoms and Possible Causes - Otolaryngology

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About sore throat?


Hello Doctor, I accidentally experienced a risky situation before, and afterwards I had painful urination, which has since resolved.
However, I have been experiencing persistent pain in the inner thigh and groin area, as well as a sore throat, for the past six months, and I have not been able to find the cause.
I have tested negative for gonorrhea, chlamydia, and HIV and syphilis after 90 days.
I have seen many doctors and have taken tetracycline and ciprofloxacin without any improvement.
My lymph nodes are not swollen.
I have consulted specialists in infectious diseases, orthopedics, otolaryngology, and urology, but no one has been able to identify the cause.
Is it possible that I have been infected by another virus? Are there more detailed tests available? The pain in my inner thigh and groin area, along with the sore throat, has persisted for six months without resolution, and the pain is so severe that it makes me feel suicidal.
The otolaryngologist only mentioned that my throat is red and swollen, but I don't understand why it hasn't improved.
How can I differentiate whether it is an infection or not? Thank you.

A-Hua, 30~39 year old female. Ask Date: 2014/06/09

Dr. Zheng Jueyi reply Otolaryngology


Hello: Given the current situation, it is recommended to continue follow-up with the Infectious Disease Department to determine if other tests should be conducted.
It may be necessary to discuss this in detail with the infectious disease physician.
Wishing you peace and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the ENT Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2014/06/09

More Info


Chronic throat pain, especially when accompanied by persistent pain in the inner thigh and groin area, can be a complex issue that requires a thorough understanding of various potential causes. Given your history of pain following a risky incident, it is important to consider both infectious and non-infectious etiologies.

Firstly, it is commendable that you have undergone extensive testing for sexually transmitted infections (STIs) such as gonorrhea, chlamydia, HIV, and syphilis, all of which returned negative. This significantly reduces the likelihood of these infections being the cause of your symptoms. However, it is still possible that other infections, including viral infections, could be at play. For instance, certain viral infections can cause persistent throat pain and may not always be detected through standard STI testing. Viruses such as Epstein-Barr virus (EBV), which causes infectious mononucleosis, or cytomegalovirus (CMV) can lead to prolonged symptoms, including sore throat and lymphadenopathy.

In addition to viral infections, other conditions could be contributing to your symptoms. For example, chronic throat pain can be associated with conditions such as gastroesophageal reflux disease (GERD), where stomach acid irritates the throat, or even allergies that cause post-nasal drip leading to throat discomfort. Furthermore, conditions like fibromyalgia or chronic fatigue syndrome can manifest as widespread pain, including in the throat and groin areas, and are often overlooked in traditional evaluations.

The persistent pain in your inner thigh and groin could also be related to musculoskeletal issues, such as muscle strain or nerve entrapment. Conditions like meralgia paresthetica, which involves compression of the lateral femoral cutaneous nerve, can cause pain in the thigh and may be exacerbated by prolonged sitting or certain positions. It is also worth considering that referred pain from other areas, such as the lower back or pelvis, could be contributing to your discomfort.

Given the duration and severity of your symptoms, it may be beneficial to pursue further evaluations. A comprehensive approach could include imaging studies such as MRI or CT scans to assess for any structural abnormalities in the pelvis or lower back that might be causing referred pain. Additionally, a referral to a pain management specialist or a rheumatologist may provide further insights, especially if a chronic pain syndrome is suspected.

In terms of managing your throat pain, it may be helpful to explore treatments beyond antibiotics, especially if bacterial infections have been ruled out. Options could include throat lozenges, saline gargles, or even corticosteroid sprays to reduce inflammation. If allergies or reflux are suspected, addressing these underlying issues could lead to significant symptom relief.

Lastly, it is crucial to address the emotional toll that chronic pain can take on mental health. Feelings of hopelessness and thoughts of self-harm are serious and should be discussed with a mental health professional. Support groups or counseling can provide valuable coping strategies and emotional support during this challenging time.

In conclusion, while the search for a definitive diagnosis can be frustrating, a multidisciplinary approach involving various specialists may help unravel the complexities of your symptoms. Persistent throat pain and associated discomfort require careful consideration of both infectious and non-infectious causes, and further evaluations may be warranted to guide effective treatment. Please ensure to communicate openly with your healthcare providers about your symptoms and any changes you experience.

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