Can Children Use Antihistamine Eye Drops Long-Term? Side Effects Explained - Pharmacology

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Inquiry about allergy eye drops?


Hello, I would like to ask a question.
My son is 5 years old and has allergy symptoms, often experiencing itchy eyes.
We visited an ophthalmologist who prescribed a bottle of "Anshumin" eye drops for us, instructing us to use it twice daily and to finish the entire bottle.
My question is, can "Anshumin" eye drops be used long-term? What side effects might it have on children?

sedc, 0~9 year old female. Ask Date: 2014/06/30

Dr. Chen Shuzi reply Pharmacology


Hello: Anshumin eye drops contain antihistamines and antibiotics per ml: Antazoline Phosphate 0.15 mg, Chlorhexidine Gluconate 0.05 mg, and Tetrahydrozoline Hydrochloride 0.5 mg.
This medication requires a prescription from a physician and is typically used 3 to 4 times a day, with 1 to 2 drops each time; for children, it is usually 1 to 2 times a day.
Indications include eye fatigue and eye allergies.
If diagnosed with eye allergies, the physician will determine the treatment duration based on the condition.
Currently, no significant side effects have been observed.

Reply Date: 2014/06/30

More Info


When it comes to the use of antihistamine eye drops in children, particularly for managing allergic symptoms, there are several important considerations regarding their long-term use and potential side effects.

Antihistamine eye drops, such as the one you mentioned ("安舒敏," which likely contains olopatadine), are commonly prescribed to alleviate symptoms of allergic conjunctivitis, including itchy and watery eyes. These medications work by blocking the action of histamine, a substance in the body that causes allergic symptoms. While they can be effective in providing relief, the question of long-term use in children is crucial.


Long-Term Use of Antihistamine Eye Drops
1. Safety and Efficacy: Antihistamine eye drops like olopatadine are generally considered safe for long-term use in children. Studies have shown that they can be used for extended periods without significant adverse effects. However, it is essential to follow the prescribing physician's guidance regarding duration and dosage.

2. Recommended Dosage: For most antihistamine eye drops, the typical recommendation is to use them twice a day. Your child's doctor has advised you to use the drops until the entire bottle is finished, which is a common practice to ensure that the symptoms are adequately managed. However, if symptoms persist or worsen, it is crucial to consult the doctor for further evaluation.

3. Monitoring: Regular follow-ups with the healthcare provider are essential to monitor the child's response to the medication and to assess whether the treatment plan needs to be adjusted. If the symptoms do not improve or if new symptoms arise, alternative treatments may be necessary.


Potential Side Effects
While antihistamine eye drops are generally well-tolerated, some potential side effects may occur, including:
1. Local Irritation: Some children may experience mild irritation, burning, or stinging upon instillation of the drops. This is usually temporary and resolves quickly.

2. Dry Eyes: Prolonged use of any eye drops can sometimes lead to dryness or discomfort in the eyes. If your child complains of dryness, it may be worth discussing with the doctor, as they may recommend artificial tears or a different treatment approach.

3. Systemic Absorption: Although rare, there is a possibility of systemic absorption of the medication, which could lead to side effects such as drowsiness or increased heart rate. However, these effects are more commonly associated with oral antihistamines rather than topical formulations.

4. Allergic Reactions: In very rare cases, a child may develop an allergic reaction to the eye drops themselves, leading to increased redness, swelling, or itching. If this occurs, it is crucial to discontinue use and seek medical advice immediately.


Conclusion
In summary, antihistamine eye drops like "安舒敏" can be used long-term in children under the guidance of a healthcare provider. While they are generally safe, it is essential to monitor for any side effects and maintain regular communication with the prescribing physician. If you have concerns about your child's symptoms or the medication's effects, do not hesitate to reach out to your healthcare provider for personalized advice and potential adjustments to the treatment plan.

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