Herpetic Pharyngitis and Prolonged Fever: When to Seek Help - Internal Medicine

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Herpetic pharyngitis with high fever?


Hello, doctor.
I started experiencing a high fever (39-40 degrees Celsius) from last Thursday, which lasted for three days, and then I developed herpetic pharyngitis.
Therefore, the doctor diagnosed it as enterovirus.
After three days of sore throat, it has gradually improved, and my average body temperature has been slightly above 37 degrees Celsius, but at night, it sometimes exceeds 38 degrees Celsius.
This has been ongoing for about a week.
Additionally, two to three days ago, I started experiencing symptoms of sneezing and a runny nose, but I have not noticed any rashes on my hands or feet.
I would like to ask the doctor: 1.
So, can "herpetic pharyngitis + high fever (39-40 degrees Celsius)" confirm a diagnosis of enterovirus, or could there be other possible conditions? 2.
I have heard that enterovirus fever typically lasts only 3-5 days.
Although I only had a high fever (39-40 degrees Celsius) for three days, I have maintained a slightly elevated temperature above 37 degrees Celsius for a week, and occasionally my temperature rises to 38 degrees Celsius at night.
Is this a normal recovery process? Under what circumstances should I return for a follow-up visit? Thank you!

A Jie, 30~39 year old female. Ask Date: 2014/07/17

Dr. Xiao Yongxun reply Internal Medicine


Herpetic pharyngitis presents with painful ulcers in specific areas of the oral cavity, accompanied by fever, sore throat, loss of appetite, general malaise, and respiratory infection symptoms.
Hand-foot-mouth disease also manifests with oral ulcers, rashes on the palms and soles, as well as fever, fatigue, and respiratory infection symptoms.
Both conditions are caused by the Coxsackie virus and belong to the enterovirus family.
Severe complications are rare, and it is recommended to maintain hydration and adequate electrolyte levels, along with sufficient sleep.
The typical duration of the illness is about 1 to 2 weeks.
However, if symptoms such as persistent high fever, altered mental status, or rapid breathing occur, it is advisable to consult your primary care physician.

Reply Date: 2014/07/17

More Info


Herpetic pharyngitis, often caused by the herpes simplex virus, can lead to significant discomfort and prolonged fever, as you've experienced. Your symptoms of high fever (39-40 degrees Celsius) followed by the development of herpetic lesions in the throat align with this diagnosis. However, it's important to clarify a few points regarding your condition and when to seek further medical help.

1. Diagnosis of Enterovirus: While herpetic pharyngitis can indeed be associated with enterovirus infections, the presence of high fever and throat lesions alone does not definitively confirm an enterovirus diagnosis. Other viral infections, such as those caused by adenoviruses or cytomegalovirus, can present similarly. A thorough clinical evaluation, including a detailed history and possibly laboratory tests, is necessary to confirm the specific viral etiology. It’s essential to consider other potential causes of your symptoms, especially if they persist or worsen.

2. Duration of Fever: It is common for viral infections to cause fever that lasts longer than the initial high fever phase. In many cases, after the acute phase of the illness, patients may experience a lingering low-grade fever as the body continues to fight off the infection. However, a fever that persists beyond a week, especially if it fluctuates or spikes at night, warrants further investigation. While some viral infections can cause prolonged symptoms, it’s crucial to monitor for any new or worsening symptoms.


When to Seek Medical Attention
You should consider returning to your healthcare provider if you experience any of the following:
- Persistent High Fever: If your fever continues to exceed 38 degrees Celsius (100.4 degrees Fahrenheit) for more than a week, or if it returns after a period of improvement, this could indicate a secondary infection or a complication.


- Severe Symptoms: If you develop severe throat pain, difficulty swallowing, or breathing difficulties, these could be signs of complications that require immediate attention.

- Neurological Symptoms: Any signs of confusion, severe headache, or changes in consciousness should prompt urgent medical evaluation.

- Dehydration: If you are unable to maintain hydration due to throat pain or other symptoms, this is another reason to seek medical help.

- Worsening Condition: If your symptoms worsen or if you develop new symptoms, such as a rash, persistent cough, or gastrointestinal issues, it’s essential to consult a healthcare professional.


Additional Considerations
In the context of viral infections, supportive care is often the mainstay of treatment. This includes:
- Hydration: Ensure you are drinking plenty of fluids to stay hydrated, especially if you have a sore throat that makes swallowing difficult.

- Pain Management: Over-the-counter medications like acetaminophen or ibuprofen can help manage fever and throat pain.

- Rest: Allow your body time to recover by getting adequate rest.

- Monitoring Symptoms: Keep a close eye on your symptoms and any changes that occur.

In conclusion, while your symptoms may align with herpetic pharyngitis and a viral infection, the persistence of fever and other symptoms necessitates careful monitoring and possibly further evaluation. If you have any concerns about your health or if your symptoms change, do not hesitate to reach out to your healthcare provider for guidance. Your health and well-being are paramount, and timely intervention can help prevent complications.

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