Can Reishi Mushroom Capsules Enhance Anticoagulant Effects? - Cardiology

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Anticoagulants and Lingzhi?


Hello, Doctor He.
I would like to ask if it is suitable for me to take reishi mushroom capsules for health purposes while I am currently on anticoagulant medication.
I have heard that reishi may enhance the effects of anticoagulants; is this true?

Yao Lin, 30~39 year old female. Ask Date: 2015/05/15

Dr. He Dongjin reply Cardiology


Patients taking anticoagulants should generally avoid combining them with other medications, especially traditional Chinese medicine such as Angelica, Ginseng, Ginkgo, Chamomile, and Reishi.
Changhua Hospital cares about your health.

Reply Date: 2015/05/15

More Info


When considering the use of Reishi mushroom (Ganoderma lucidum) capsules while on anticoagulant medications, it is essential to understand the potential interactions and effects that this supplement may have on your health. Reishi mushrooms are known for their various health benefits, including immune system support and potential anti-inflammatory properties. However, they also have anticoagulant effects, which means they can thin the blood and may enhance the effects of anticoagulant medications.

Anticoagulants, such as warfarin, dabigatran, rivaroxaban, and others, are prescribed to prevent blood clots and reduce the risk of stroke and heart attack. When taken together with supplements that have blood-thinning properties, there is a risk of excessive bleeding or bruising. This is particularly concerning if you are already on a prescribed anticoagulant regimen, as the combined effects could lead to complications.

Research has shown that certain compounds found in Reishi mushrooms, such as triterpenes and polysaccharides, can influence blood coagulation. While some studies suggest that Reishi may have a mild anticoagulant effect, the extent of this effect can vary based on the dosage and the individual’s health status. Therefore, it is crucial to approach the use of Reishi mushrooms with caution if you are currently taking anticoagulant medications.

Here are some key points to consider:
1. Consult Your Healthcare Provider: Before adding any new supplement, including Reishi mushroom capsules, to your regimen, it is vital to discuss it with your healthcare provider. They can provide personalized advice based on your medical history, current medications, and overall health.

2. Monitor for Signs of Bleeding: If you and your healthcare provider decide that it is safe for you to take Reishi mushrooms, be vigilant for any signs of increased bleeding. Symptoms may include unusual bruising, prolonged bleeding from cuts, or blood in urine or stool. If you notice any of these symptoms, contact your healthcare provider immediately.

3. Dosage Considerations: If you do proceed with taking Reishi, ensure that you are using it at a safe dosage. High doses of any supplement can lead to adverse effects, and the interaction with anticoagulants may be dose-dependent.

4. Research and Evidence: While there is some evidence supporting the anticoagulant properties of Reishi mushrooms, more research is needed to fully understand their effects, especially in individuals taking anticoagulant medications. The variability in individual responses to supplements also complicates the matter.

5. Alternative Options: If you are looking for health benefits without the risk of interaction, consider discussing alternative supplements or lifestyle changes with your healthcare provider that may support your health without affecting your anticoagulant therapy.

In summary, while Reishi mushrooms may offer health benefits, their potential to enhance the effects of anticoagulant medications warrants caution. Always consult with your healthcare provider before making any changes to your medication or supplement regimen to ensure your safety and well-being.

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