Peeling After Applying Medication on the Glans: Causes and Solutions - Urology

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After applying medication to the glans, there may be complete peeling of the skin?


Hello Doctor: I previously inquired about the issue of prolonged exposure of the glans leading to roughness (the glans became dry and rough due to prolonged exposure).
Last Saturday, I visited the hospital, and the doctor diagnosed me with mild inflammation (redness) at the urethral opening and prescribed Mecon Cream to apply on the glans.
I have been following the instructions to apply it every morning and evening.
After applying it, the glans feels much better and is no longer dry and rough like before.
However, since yesterday, I have noticed peeling in the glans area, where the skin can be removed in large pieces, appearing milky white and somewhat thick.
The surface underneath feels normal, without any redness or discomfort, and the areas that have peeled off are not painful or itchy.
Additionally, I have experienced peeling for two consecutive days.
Currently, I do not have any pain during urination.

I have a few questions:
(1) When I apply the cream, it tends to be a bit thick.
Is this peeling likely a result of the cream forming a membrane, or could there be a possibility of a true infection of the glans? How can this peeling be diagnosed? What can I do to help the doctor determine whether this is a medication-related membrane or another infection?
(2) The doctor who prescribed the medication seems to be on leave this week, and I won’t be able to consult him directly until next Saturday.
If necessary, should I seek another doctor’s opinion this week? If so, should I simply inform them of the situation as it is?
(3) Should I continue using the cream?

Wei Ni, 20~29 year old female. Ask Date: 2015/05/28

Dr. Xu Weikai reply Urology


Winnie: Hello! 1.
It could be due to an ointment or the adhesion of some epithelial cells.
Generally, after the glans undergoes desquamation, it becomes very red and painful, and in severe cases, it may even bleed.
2.
You can stop using the medication to see if the symptoms persist.
3.
Of course, when you return for a follow-up, you should inform the physician.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Answers found online should only be used as a reference; if necessary, it is still important to seek medical attention at a healthcare facility.
The Ministry of Health and Welfare Taitung Hospital cares about you.

Reply Date: 2015/05/28

More Info


Understanding the peeling of the glans after applying medication, particularly in the context of using a topical cream like Meikang ointment, can be a source of concern for many patients. Based on your description, it seems that you are experiencing a peeling reaction after applying the ointment, which is a common occurrence when using topical medications, especially those that are designed to treat inflammation or irritation.

1. Peeling as a Reaction: The peeling you are experiencing could be attributed to several factors. One possibility is that the ointment is causing a mild exfoliation of the skin on the glans. This can happen as the medication works to heal the underlying inflammation. The thick, white, and somewhat adherent layer you describe may indeed be a result of the ointment forming a protective barrier over the inflamed area, which can sometimes lead to superficial skin layers shedding as they heal. It is also possible that the ointment is causing a mild irritation or allergic reaction, although you mentioned that there is no pain or itching, which makes this less likely.

2. Diagnosis and Monitoring: To help your physician determine whether the peeling is due to the medication or an underlying infection, you can monitor the following:
- Appearance: Note if the peeling is accompanied by any redness, swelling, or discharge. If the surface underneath the peeling skin appears normal and healthy, it is likely a reaction to the ointment rather than an infection.

- Duration: Keep track of how long the peeling lasts. If it resolves within a few days and the underlying skin appears healthy, it is likely a benign reaction.

- Symptoms: Since you are not experiencing any pain or urinary issues, this is a positive sign. However, if you notice any new symptoms, such as increased redness, swelling, or discomfort, it would be prudent to seek medical advice sooner.

3. Follow-Up with Your Doctor: Given that your prescribing physician is unavailable this week, it is advisable to wait until you can see them unless your symptoms worsen. If you feel uncertain or if the peeling continues without improvement, seeking a second opinion from another healthcare provider is a reasonable option. When you do consult with another physician, be sure to provide a detailed account of your symptoms, the medication used, and the timeline of your treatment.

4. Continued Use of the Ointment: As for whether to continue using the ointment, it is generally advisable to follow the instructions given by your physician unless you experience adverse reactions. Since you mentioned that the ointment has helped alleviate the initial dryness and roughness, it may be beneficial to continue using it while monitoring the peeling. However, if the peeling worsens or if you develop any new symptoms, it would be wise to stop using the ointment and consult a healthcare professional.

In summary, the peeling you are experiencing could be a normal reaction to the medication as it works to heal the area. Monitoring the situation and maintaining communication with your healthcare provider is essential. If you have any concerns or if the condition changes, do not hesitate to seek medical advice sooner. Your health and comfort are paramount, and addressing any issues promptly can help ensure a smoother recovery.

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