Post-Antibiotic Urine Test: When to Follow Up for Kidney Stones? - Urology

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Urinary Tract Stone Issues 3


Responder: Taoyuan Hospital / Urology / Dr.
Fu Shih-Chang, 2015/06/23 "Question / More questions answered by this physician" Of course, you should return for a follow-up after completing the antibiotic course.
Hello, what I mean is, can I come back for a urine test the day after finishing the antibiotics to check if the inflammation and hematuria have improved? I'm concerned that the presence of antibiotics in my system might affect the accuracy of the test, and the doctor might not want to perform the test, which would make the trip unnecessary.
Thank you for your patient response.

Mr. Li, 20~29 year old female. Ask Date: 2015/06/23

Dr. Fu Shizhang reply Urology


This is not a problem; you can rest assured!

Reply Date: 2015/06/23

More Info


When dealing with kidney stones and urinary tract infections (UTIs), the timing of urine tests after antibiotic treatment is crucial for accurate diagnosis and management. It is generally recommended to wait until after completing a course of antibiotics before undergoing a follow-up urine test. This is because antibiotics can significantly alter the composition of urine, potentially masking the presence of bacteria or other indicators of infection, thus leading to misleading results.

Antibiotics work by targeting and eliminating bacteria, which can reduce the levels of white blood cells and other markers of infection in the urine. If you were to test your urine while still on antibiotics, you might not see the expected signs of infection, such as the presence of nitrites, leukocyte esterase, or a high white blood cell count. This could lead your physician to incorrectly conclude that the infection has resolved when, in fact, it may still be present.

In your case, it would be prudent to wait until you have completed your antibiotic regimen and allow a short period for the medication to clear from your system before returning for a urine test. This waiting period can help ensure that the test results reflect your true urinary status without the interference of antibiotics. Typically, waiting 24 to 48 hours after finishing antibiotics is a reasonable timeframe to allow for accurate testing.

Regarding kidney stones, if you have been experiencing symptoms such as hematuria (blood in urine) or flank pain, it is essential to monitor these symptoms closely. If you notice persistent symptoms or if new symptoms arise, it may warrant an earlier follow-up with your healthcare provider. In cases where kidney stones are suspected, imaging studies such as ultrasound or CT scans may be necessary to assess the presence and size of stones, especially if symptoms persist despite treatment.

In terms of managing kidney stones, hydration is key. Drinking plenty of fluids helps dilute the urine and can facilitate the passage of small stones. For stones that are less than 5 mm in size, there is a high likelihood of spontaneous passage, especially with adequate hydration. However, larger stones may require medical intervention, such as lithotripsy or ureteroscopy, depending on their size and location.

If you have a history of recurrent kidney stones, it is also important to discuss preventive measures with your healthcare provider. Dietary modifications, such as reducing sodium intake, limiting foods high in oxalates (like spinach and nuts), and ensuring adequate calcium intake, can help reduce the risk of stone formation. Additionally, some studies suggest that citrate, found in lemon juice, may help prevent stone formation by binding calcium in the urine.

In summary, for accurate urine test results post-antibiotic treatment, it is advisable to wait until the antibiotics have cleared from your system. If you have ongoing symptoms or concerns about kidney stones, follow up with your healthcare provider for further evaluation and management. Maintaining good hydration and discussing dietary strategies can also play a significant role in preventing future stone formation.

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