Managing BXO: Treatment Options for Balanitis Xerotica Obliterans - Urology

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BXO, or Balanitis Xerotica Obliterans?


Hello, Dr.
Lee! I would like to ask about a condition diagnosed three years ago as chronic balanitis due to a biopsy of the coronal sulcus.
I understand that the cause is unknown and it cannot be completely cured, but I have not experienced any issues in the past three years.
There are no so-called white spots on the foreskin, but I have noticed some changes in the glans, including a few red spots and a shiny, smooth appearance, which seems somewhat abnormal.
If it cannot be cured, are there any specific medications to help control its worsening? I am already aware of all the cleaning protocols.
Should I see a urologist for this? In the absence of any significant changes, is it advisable to avoid continuous application of steroid medications? I am concerned about the potential for worsening.
Thank you!

Tony, 60~69 year old female. Ask Date: 2015/07/01

Dr. Li Xinyi reply Urology


It may be related to autoimmunity.
It is still important to focus on a healthy immune system through proper diet, exercise, and a healthy lifestyle, as the cause remains unclear and effective recommendations cannot be made.

Reply Date: 2015/07/01

More Info


Balanitis Xerotica Obliterans (BXO), also known as Lichen Sclerosus, is a chronic inflammatory condition that primarily affects the genital area, particularly the glans penis and foreskin. It is characterized by white patches, thinning of the skin, and can lead to scarring and narrowing of the urethral opening if left untreated. While the exact cause of BXO remains unclear, it is believed to involve an autoimmune component, and it can be associated with other autoimmune diseases.

Given your history of a confirmed diagnosis three years ago and the absence of significant symptoms since then, it is encouraging that you have not experienced any major flare-ups. However, the changes you describe, such as red spots and a shiny appearance of the glans, warrant careful monitoring.

Treatment Options
1. Topical Corticosteroids: These are the first-line treatment for BXO. They help reduce inflammation and can prevent the progression of the disease. However, it is essential to use them judiciously. Continuous long-term use of potent topical steroids can lead to skin thinning and other side effects. It is generally recommended to use them intermittently or during flare-ups rather than continuously. If you are concerned about the potential for worsening your condition, it would be wise to discuss a tapering schedule with your healthcare provider.

2. Emollients and Moisturizers: Regular use of emollients can help maintain skin hydration and barrier function. This can be particularly beneficial in preventing irritation and maintaining skin integrity.

3. Immunomodulators: In cases where corticosteroids are ineffective or if there are concerns about long-term use, other medications such as tacrolimus or pimecrolimus (topical calcineurin inhibitors) may be considered. These can help manage inflammation without the side effects associated with long-term steroid use.

4. Surgical Options: In severe cases where scarring or phimosis (tight foreskin) occurs, surgical intervention may be necessary. This could involve circumcision or other procedures to relieve symptoms and prevent complications.


Monitoring and Follow-Up
It is crucial to have regular follow-ups with a urologist or dermatologist who specializes in genital skin conditions. They can monitor any changes in your condition and adjust treatment as necessary. If you notice any new symptoms, such as increased redness, pain, or discharge, it is essential to seek medical attention promptly.


Hygiene and Care
While you mentioned being aware of cleaning protocols, maintaining good hygiene is vital in managing BXO. Gentle cleansing with mild soap and water, avoiding irritants, and ensuring the area is dry can help prevent secondary infections and irritation.


Conclusion
In summary, while BXO may not be curable, it can be effectively managed with appropriate treatment strategies. Regular monitoring and a tailored approach to your treatment plan are essential. If you have concerns about the use of topical steroids or any other medications, discussing these with your urologist will help you make informed decisions about your care. Remember, proactive management is key to preventing complications and maintaining quality of life.

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