HSV IgG Test Results: What Do the Numbers Mean? - Urology

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HSV IgG test values


Hello Doctor: I previously inquired about the appearance of blisters on the surface of the glans.
Although I have not engaged in sexual intercourse, both the clinic and online resources suggested that it could possibly be herpes based on the images I provided.
(Images at: http://imgur.com/lzNui0K http://imgur.com/0PJZovw http://imgur.com/rtJ1Vc4 http://imgur.com/q5SLfR5) Since the clinic I visited did not have a laboratory, I underwent two HSV tests in the 4th and 6th weeks after the blisters appeared.
The first test showed HSV II IgG at 1.71 (-) (I did not consider the possibility of HSV I at that time, so I did not test for it).
The second test showed HSV I IgG at 3.32 (-) and HSV II IgG at 1.53 (-).
The reference values are <16 (-); >22 (+); 16-22 (+/-) RU/mL.
I would like to ask, although the test results are all negative, the value for HSV I seems to be relatively higher.
What is the significance of this? Should I just monitor the situation to see if there are any recurrences? @@

Wei Ni, 20~29 year old female. Ask Date: 2015/07/09

Dr. Xu Weikai reply Urology


A negative test result is simply negative.
For example, let's say that based on your height, your standard weight is between 50 to 70 kilograms.
If you weigh 51 kilograms today, do you consider your weight to be normal? And if you measure your weight at 69 kilograms, do you think that is abnormal? If there are any unclear points, feel free to ask again, and we can discuss and research further.
Answers found online should only be used as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
The Ministry of Health and Welfare Taitung Hospital cares about you.

Reply Date: 2015/07/09

More Info


Understanding the results of an HSV (Herpes Simplex Virus) IgG test can be quite complex, especially when considering the implications for your health and potential transmission to partners. The IgG test is designed to detect antibodies that your body produces in response to an HSV infection. There are two types of herpes simplex viruses: HSV-1 and HSV-2. Typically, HSV-1 is associated with oral herpes, while HSV-2 is more commonly linked to genital herpes.

In your case, the results you provided indicate that both HSV-IgG and HSV-IIgG tests returned negative results, with values of 1.71 and 1.53 respectively, which are below the threshold for a positive result (16 RU/mL). This suggests that you do not currently have an active infection with either type of herpes simplex virus. The fact that your results are negative is reassuring, especially considering your concerns about potential transmission and future outbreaks.

The numbers you mentioned, particularly the HSV-IgG value of 3.32, while still negative, indicate that there may have been some exposure to the virus in the past, but not enough to produce a positive result. It's important to note that the presence of antibodies does not necessarily correlate with active symptoms or outbreaks. Many individuals who test positive for HSV may never experience symptoms, and those who do may have infrequent outbreaks.

Regarding your concern about the possibility of future outbreaks or transmission to partners, it's essential to understand that while the virus can remain dormant in the body, not everyone who has been exposed will experience recurrent outbreaks. Factors such as stress, illness, and immune system function can influence the likelihood of an outbreak. If you are asymptomatic and your tests are negative, the risk of transmission is significantly lower.

As for your question about the reference values and the significance of the numbers, it is crucial to remember that different laboratories may have varying reference ranges and testing methodologies. Therefore, while your results may show slight variations, the key takeaway is that they are all within the negative range, indicating no current infection.

If you are still experiencing symptoms, such as the water blisters you mentioned, it may be worthwhile to consult with a healthcare provider for further evaluation. They may recommend additional tests or examinations to determine the cause of your symptoms, as they could be related to other conditions that are not necessarily linked to HSV.

In summary, your HSV IgG test results indicate that you do not have an active herpes infection at this time. The presence of low-level antibodies suggests past exposure but does not confirm an active infection. If you have concerns about future outbreaks or transmission, consider discussing these with a healthcare professional who can provide personalized advice based on your health history and current situation. Regular check-ups and open communication with sexual partners about STI testing can also help manage risks and promote sexual health.

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