Persistent Itching: Is It Urticaria or Something Else? - Dermatology

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Skin itching


Hello, recently (for over a week) I have been experiencing intermittent itching all over my body, sometimes to the point where I can't sleep.
The appearance of my skin shows no rashes or erythema; only after scratching do I notice scratch marks and irregular red spots.
Could this be considered urticaria? My impression of urticaria is that it presents with raised red welts on the skin.
Or could it be another condition? What tests should I undergo, such as blood tests?

Xuan, 10~19 year old female. Ask Date: 2015/07/13

Dr. Wu Yuxin reply Dermatology


A medical consultation is necessary, as the absence of a rash makes diagnosis more challenging.
Sometimes, blood tests are indeed required to assist in the diagnosis.

Reply Date: 2015/07/13

More Info


Persistent itching, especially when it occurs without visible rashes or lesions, can be quite distressing and may lead to concerns about underlying conditions. In your case, the absence of red rashes or hives, along with the presence of scratch marks and irregular red spots after scratching, suggests that this may not be classic urticaria (hives). Urticaria typically presents as raised, itchy welts on the skin that can vary in size and shape, often accompanied by redness and swelling.
Given your symptoms, there are several potential causes for your persistent itching. Here are some possibilities:
1. Chronic Idiopathic Urticaria: This condition can cause itching without the typical wheals or hives. It is termed "idiopathic" because the exact cause is often unknown. It can be triggered by various factors, including stress, temperature changes, or even certain foods.

2. Dry Skin (Xerosis): Dry skin is a common cause of itching, especially in colder months or in individuals who may not be adequately hydrating their skin. This can lead to a sensation of itchiness without any visible rash.

3. Allergic Reactions: Allergies to food, medications, or environmental factors (like pollen or pet dander) can cause itching. Sometimes, the skin may not show visible signs of an allergic reaction, especially in cases of delayed hypersensitivity.

4. Dermatological Conditions: Conditions such as eczema or psoriasis can cause itching, even if the skin appears normal at times. These conditions can have periods of flare-ups and remissions.

5. Systemic Conditions: Certain systemic diseases, such as liver disease, kidney disease, or thyroid disorders, can manifest as generalized itching. In these cases, the itchiness is often accompanied by other symptoms related to the underlying condition.

6. Psychogenic Itch: Stress and anxiety can also lead to sensations of itching without any dermatological cause. This is often referred to as psychogenic itch.

Given the duration of your symptoms (over a week) and their impact on your sleep, it is advisable to seek medical evaluation. A healthcare provider may recommend several diagnostic tests, including:
- Blood Tests: These can help rule out systemic conditions, check for liver and kidney function, and assess for any signs of infection or inflammation.

- Allergy Testing: If an allergic reaction is suspected, skin prick tests or specific IgE blood tests may be performed to identify potential allergens.

- Skin Biopsy: In some cases, a dermatologist may recommend a skin biopsy to examine the skin more closely if other conditions are suspected.

In the meantime, consider the following self-care measures to alleviate your symptoms:
- Moisturize: Regularly apply a fragrance-free moisturizer to keep your skin hydrated.

- Avoid Irritants: Identify and avoid any known irritants, such as harsh soaps, detergents, or fabrics that may exacerbate your itching.

- Cool Compresses: Applying cool compresses to the affected areas can provide temporary relief from itching.

- Antihistamines: Over-the-counter antihistamines may help reduce itching, especially if there is a possibility of an allergic component.

In conclusion, while your symptoms may not align perfectly with urticaria, they warrant further investigation to determine the underlying cause. Consulting with a healthcare professional will provide you with a tailored approach to diagnosis and management.

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