Does Reducing Prolactin Levels with Medication Cause Breast Size Decrease? - Obstetrics and Gynecology

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Will taking medication to lower elevated prolactin levels cause breast size to decrease?


Hello Doctor, I went to the hospital for blood tests and an ultrasound due to irregular menstruation.
The ultrasound results showed that my uterine and ovarian functions are normal, but my prolactin levels are elevated, and I am not ovulating.
The doctor prescribed me Dostinex.
I read online that taking this medication might cause breast size reduction (I don't want to lose breast size, crying).
I'm wondering if the decrease in prolactin secretion will lead to a reduction in breast size as well.
Thank you, Doctor!

Miss Wang, 20~29 year old female. Ask Date: 2015/07/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, I hope not.
Wishing you good health.

Reply Date: 2015/07/20

More Info


Reducing prolactin levels with medication, such as Dostinex (cabergoline), can indeed have various effects on the body, but the relationship between prolactin levels and breast size is not straightforward. Prolactin is a hormone produced by the pituitary gland, primarily responsible for milk production in women after childbirth. Elevated levels of prolactin, known as hyperprolactinemia, can lead to various symptoms, including irregular menstrual cycles, galactorrhea (milk production not associated with childbirth), and even breast tenderness.

When prolactin levels are reduced through medication, some individuals may notice changes in breast tissue. This is because prolactin plays a role in breast development and maintenance. However, the extent to which breast size may decrease varies from person to person and is not guaranteed. In many cases, the reduction in breast size is minimal and may not be noticeable. It is also important to consider that breast size can be influenced by various factors, including hormonal changes, body weight, and genetics.

In your case, since you are taking Dostinex to manage high prolactin levels and irregular menstrual cycles, it is understandable to be concerned about potential changes in breast size. However, it is essential to focus on the primary goal of the treatment, which is to restore hormonal balance and alleviate symptoms associated with hyperprolactinemia. If you experience any significant changes or side effects while on the medication, it is crucial to discuss these with your healthcare provider.

Regarding Dostinex, it is generally well-tolerated, but like any medication, it can have side effects. Common side effects include nausea, headache, dizziness, and fatigue. Some individuals may also experience gastrointestinal disturbances. Serious side effects are rare but can include heart valve problems, particularly in those with a history of heart disease. It is essential to have regular follow-ups with your doctor to monitor your response to the medication and any potential side effects.

If you are particularly concerned about breast size changes, it may be helpful to discuss this with your healthcare provider. They can provide you with more personalized information based on your medical history and current health status. Additionally, if you have any underlying concerns about breast health, such as family history of breast cancer, it is vital to communicate this to your doctor, as they may recommend regular screenings or additional evaluations.

In summary, while reducing prolactin levels with medications like Dostinex can potentially influence breast size, the extent of this change is highly individual and may not be significant. The primary focus should be on managing your hormonal health and addressing any symptoms related to high prolactin levels. Always consult with your healthcare provider regarding any concerns or side effects you may experience during treatment.

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Dr. Zhang Kunmin reply Obstetrics and Gynecology
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Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, a value of 39 is not high and may be related to your constitution. If your menstruation has not occurred, it is advisable to take medication to lower prolactin levels. Wishing you good health.

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