Can I Take Two Antihistamine Tablets at Night for Chronic Hives? - Pharmacology

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When dealing with chronic hives, also known as chronic urticaria, it is crucial to manage symptoms effectively while ensuring that medication use is safe and appropriate. In your case, you are currently prescribed an antihistamine, specifically "Chuang Ning" (which contains 10mg of an antihistamine), to be taken twice daily—once in the morning and once in the evening. However, you are experiencing significant flare-ups of hives at night, leading you to consider taking both doses in the evening.

Firstly, it is important to understand how antihistamines work. Antihistamines block the action of histamine, a substance in the body that causes allergic symptoms. By taking them regularly, you can help prevent the symptoms associated with allergies, including hives. However, taking more than the prescribed dosage or altering the timing of your doses should be done cautiously and ideally under the guidance of your healthcare provider.

In general, taking both doses of your antihistamine at night may provide temporary relief from nighttime symptoms, but it is essential to consider a few factors:
1. Dosage and Timing: While you may be tempted to take both doses at night, it is typically recommended to space out antihistamine doses to maintain a steady level of the medication in your system. Taking both doses at once could lead to increased sedation and other side effects, especially if the antihistamine you are taking has sedative properties.

2. Potential Side Effects: Antihistamines can cause drowsiness, dizziness, and dry mouth. If you take both doses at night, you may experience heightened drowsiness, which could affect your ability to wake up in the morning or perform daily activities.
3. Empty Stomach Considerations: Taking antihistamines on an empty stomach can sometimes lead to gastrointestinal discomfort, but this varies by individual and the specific medication. It is generally advisable to take medications with food to minimize potential stomach irritation unless otherwise directed by your healthcare provider.

4. Consult Your Doctor: Before making any changes to your medication regimen, it is crucial to consult with your healthcare provider. They may suggest adjusting your dosage, changing the timing of your doses, or even trying a different antihistamine that may be more effective for your nighttime symptoms.

5. Alternative Treatments: If your hives are particularly troublesome at night, your doctor might consider additional treatments or medications, such as a stronger antihistamine or corticosteroids, depending on the severity of your symptoms and your overall health profile.

In summary, while it may seem reasonable to take both doses of your antihistamine at night to combat your chronic hives, it is essential to approach this change with caution. Always consult your healthcare provider before making any adjustments to your medication regimen to ensure that you are managing your symptoms safely and effectively. They can provide personalized advice based on your specific situation and health history.