Effects of Anesthesia During Conception and Cervical Cancer Vaccine Concerns - Obstetrics and Gynecology

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If anesthesia is administered during the conception period and pregnancy occurs during that time, will it have any effects?


Hello Dr.
Tsao, I would like to ask if there are any effects if anesthesia (such as sedation for gastroscopy and colonoscopy) is administered during the conception period and if pregnancy occurs during that time.
Additionally, I just received the first dose of the cervical cancer vaccine; what effects might there be if I become pregnant while waiting for the second dose?

lin, 30~39 year old female. Ask Date: 2015/08/13

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if anesthesia was administered during the conception period (such as during a painless gastroscopy or colonoscopy), it generally does not have a significant impact if pregnancy occurs during that time.
However, if pregnancy is confirmed, it is not recommended to receive the cervical cancer vaccine.
Wishing you good health.

Reply Date: 2015/08/13

More Info


When considering the effects of anesthesia during conception and the implications of receiving the cervical cancer vaccine while pregnant, it's essential to understand both the safety of the procedures involved and the potential risks to the developing fetus.

Firstly, regarding the use of anesthesia during procedures such as gastroscopy and colonoscopy, it is generally considered safe when performed in early pregnancy. Most studies indicate that the use of anesthesia in non-emergency situations does not significantly increase the risk of adverse outcomes for the fetus. However, it is crucial to inform your healthcare provider if you suspect you are pregnant or if you find out you are pregnant after undergoing such procedures. In such cases, they may recommend additional monitoring or precautions.

As for the cervical cancer vaccine, specifically the HPV vaccine, it is recommended that women avoid getting vaccinated while pregnant. The vaccine is not contraindicated in women who become pregnant after receiving the first dose, but it is advisable to wait until after the pregnancy to complete the vaccination series. The reason for this caution is primarily due to the lack of extensive studies on the effects of the vaccine during pregnancy. Although no significant adverse effects have been reported, the vaccine's safety profile in pregnant women is not fully established.

If you have already received the first dose of the HPV vaccine and then discover you are pregnant, it is generally recommended to postpone the second dose until after the pregnancy. The rationale behind this recommendation is to minimize any potential risks, even if they are not well-documented. The HPV vaccine is designed to prevent cervical cancer and other HPV-related diseases, and completing the vaccination series is important for long-term protection. However, the health and safety of both the mother and the developing fetus take precedence.

In summary, while the use of anesthesia during early pregnancy is typically safe, it is always best to consult with your healthcare provider regarding any procedures you may need. If you find out you are pregnant after receiving the first dose of the cervical cancer vaccine, it is advisable to wait until after your pregnancy to receive the second dose. Always communicate openly with your healthcare providers about your medical history and any concerns you may have regarding pregnancy, anesthesia, and vaccinations. They can provide personalized advice based on your specific situation and health needs.

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