Progesterone Use in Early Pregnancy After Miscarriage - Obstetrics and Gynecology

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Could you please clarify your question regarding progesterone?


Hello, doctor.
I previously experienced a natural miscarriage at six weeks.
This time, I started feeling discomfort at four weeks and was worried it might be the same, so at five weeks, the doctor prescribed Prometrium (progesterone) to take one tablet three times a day, advising me to continue until the next appointment at eight weeks to check for a heartbeat.
However, at six weeks, the gestational sac measured only 0.7 cm, which seems small.
Additionally, my breast tenderness has disappeared.
Currently, at seven weeks, I have no discomfort and no symptoms.
Should I continue taking the progesterone? If I keep taking it and the embryo is not developing properly, will it prevent a natural miscarriage? Thank you.

sa, 30~39 year old female. Ask Date: 2015/09/09

Dr. Lü Lizheng reply Obstetrics and Gynecology


1.
To assess abnormal embryonic development, ultrasound can be utilized.
Generally, abdominal ultrasound can detect a heartbeat at six to seven weeks of gestation.
If there is no heartbeat detected, it may indicate abnormal embryonic development.
Additionally, monitoring the rate of embryonic growth is important; if there is a consistent lack of growth, it may also suggest abnormal development.
It is advisable to discuss these findings with a physician for further confirmation.
2.
At six weeks, the gestational sac measures only 0.7 cm, which is smaller than the average size.
However, this could also be due to measurement error or miscalculation of gestational age.
It is recommended to continue monitoring the rate of embryonic development for further assessment.
Sincerely, Dr.
Li-Cheng Lu, Taoyuan Hospital.

Reply Date: 2015/09/09

More Info


Understanding the use of progesterone in early pregnancy, especially after a miscarriage, is a critical topic for many expecting mothers. Progesterone is a hormone that plays a vital role in maintaining pregnancy, particularly in the early stages. It helps prepare the uterine lining for the implantation of the embryo and supports the pregnancy by preventing uterine contractions that could lead to miscarriage.

In your case, having experienced a natural miscarriage at six weeks previously, it is understandable that you are concerned about your current pregnancy. Your doctor has prescribed Promone (a form of micronized progesterone) to help support your pregnancy, especially since you began experiencing discomfort at four weeks. The recommendation to continue taking progesterone until your next appointment at eight weeks is common practice, particularly for women with a history of miscarriage or those experiencing early pregnancy complications.

Regarding your concerns about the size of the gestational sac (0.7 cm at six weeks) and the absence of symptoms like breast tenderness, it is important to remember that every pregnancy is unique. While the size of the gestational sac can be an indicator of viability, it is not the sole determinant. Some pregnancies may develop normally despite initial measurements that seem small. The absence of symptoms can also be normal, as pregnancy symptoms can vary widely among women and even from one pregnancy to another.

Continuing progesterone supplementation can be beneficial, especially if there is a concern about the stability of the pregnancy. However, it is crucial to have open communication with your healthcare provider. They can monitor your hormone levels and the development of the embryo through ultrasound and blood tests. If the embryo is not developing as expected, your doctor will discuss the best course of action with you.

As for your question about whether continuing progesterone could prevent a natural miscarriage if the embryo is not viable, it is essential to understand that progesterone supports the pregnancy but does not change the viability of the embryo itself. If there is a chromosomal abnormality or other issues with the embryo, progesterone will not prevent a miscarriage from occurring. The body will naturally expel a non-viable pregnancy when it is ready, regardless of progesterone supplementation.

In summary, it is crucial to follow your doctor's advice regarding progesterone use, especially given your history. Regular monitoring through ultrasounds and blood tests will provide more information about the health of your pregnancy. If you have any concerns or experience any new symptoms, do not hesitate to reach out to your healthcare provider for guidance. They are best equipped to support you through this process and ensure the health and safety of both you and your developing baby.

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