Post-Cryotherapy Symptoms for Plantar Warts - Dermatology

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Treatment of plantar warts?


I have been undergoing cryotherapy for warts on the sole of my foot for some time now (still in treatment).
I want to ask if it is normal for the area around the wound to have small, flat, blister-like formations, and for the untreated surrounding skin to be itchy.
I asked my dermatologist, and he said this is normal, but I still find it a bit strange and wanted to check.

Ting, 20~29 year old female. Ask Date: 2015/09/22

Dr. Li Yufen reply Dermatology


Hello: After cryotherapy, it is possible for blisters to form on the skin.
As long as the blisters are not too large and do not interfere with normal activities, you can allow them to dry out and fall off naturally.
Thank you!

Reply Date: 2015/09/22

More Info


After undergoing cryotherapy for plantar warts, it's not uncommon to experience a variety of symptoms as part of the healing process. Cryotherapy involves applying extreme cold to the wart, which causes the tissue to freeze and eventually die off. This treatment can lead to a range of post-treatment effects, including the formation of blisters, itching, and changes in the surrounding skin.

The appearance of small, flat, blister-like formations around the treated area is generally a normal response to cryotherapy. These can be referred to as "serous blisters," which are filled with a clear fluid and can occur as the skin reacts to the trauma of the freezing process. The skin around the wart may also itch as it heals, which is a common symptom of the body’s inflammatory response. This itching can be attributed to the release of histamines and other inflammatory mediators as the body begins to repair the damaged tissue.

While your dermatologist has indicated that these symptoms are normal, it’s important to monitor them closely. Here are a few points to consider regarding your situation:
1. Healing Process: After cryotherapy, the treated area typically goes through several stages of healing. Initially, you may notice redness and swelling, followed by blister formation. As the area heals, the blisters may dry out and form a scab, which is part of the natural healing process.

2. Itching: Itching is a common symptom during the healing phase. It can be caused by the regeneration of skin cells and the healing of the underlying tissues. However, excessive itching or discomfort may warrant further evaluation, especially if it becomes severe or is accompanied by other symptoms such as increased redness, warmth, or discharge.

3. Infection Risk: While the symptoms you describe are typically normal, it’s crucial to keep an eye out for signs of infection. If you notice increased pain, swelling, pus, or a fever, you should contact your healthcare provider immediately. Infections can complicate the healing process and may require additional treatment.

4. Follow-Up Care: It’s essential to follow any aftercare instructions provided by your dermatologist. Keeping the area clean and protected can help prevent complications. If the symptoms persist or worsen, or if you have any concerns about the healing process, don’t hesitate to reach out to your healthcare provider for further evaluation.

5. Alternative Treatments: If you find that the cryotherapy is not yielding the desired results or if the side effects are bothersome, discuss alternative treatment options with your dermatologist. There are various methods for treating plantar warts, including topical treatments, laser therapy, and immunotherapy.

In summary, while the symptoms you are experiencing after cryotherapy for plantar warts can be considered normal, it’s important to remain vigilant and proactive about your healing process. If you have any doubts or if your symptoms change, consulting with your dermatologist or healthcare provider is the best course of action. They can provide personalized advice and ensure that your recovery proceeds smoothly.

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