How Many More Chemotherapy Sessions Are Needed After Surgery for Ewing's Sarcoma? - Oncology

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Number of chemotherapy sessions


Hello, doctor.
I have Ewing's sarcoma and have undergone four rounds of chemotherapy before my surgery, which has now been completed.
I also had a CT scan, and the doctor said my lungs are clear.
How many more rounds of chemotherapy do I need to undergo?

Yingzi, 10~19 year old female. Ask Date: 2015/09/25

Dr. Lai Yicheng reply Oncology


Hello: Regarding your question, it is necessary to discuss the follow-up treatment with the attending physician, and regular monitoring will still be required.
This is from Director Lai of the Oncology Department at Changhua Hospital.

Reply Date: 2015/09/25

More Info


Ewing's sarcoma is a rare and aggressive type of bone cancer that primarily affects children and young adults. The treatment approach for Ewing's sarcoma typically involves a combination of chemotherapy, surgery, and sometimes radiation therapy. The number of chemotherapy sessions required after surgery can vary significantly based on several factors, including the initial response to chemotherapy, the extent of the disease, and the specific treatment protocol being followed.

In your case, since you have undergone four cycles of chemotherapy prior to surgery and the CT scan shows no evidence of metastasis in the lungs, this is a positive indicator. Generally, the treatment plan for Ewing's sarcoma often includes additional chemotherapy after surgery to eliminate any remaining cancer cells and reduce the risk of recurrence. This post-operative chemotherapy is sometimes referred to as "adjuvant chemotherapy."
The standard protocol for Ewing's sarcoma typically involves a total of 6 to 8 cycles of chemotherapy, which may be divided into pre-operative (neoadjuvant) and post-operative (adjuvant) treatments. Since you have already completed four cycles before surgery, it is likely that your oncologist will recommend an additional 2 to 4 cycles of chemotherapy after surgery, depending on the specific treatment regimen and your individual response to the initial treatment.

It's crucial to have an open discussion with your oncologist about your treatment plan. They will consider various factors, including your overall health, the pathology results from the surgery, and any potential side effects you may have experienced during the initial chemotherapy. The oncologist may also perform additional imaging studies or blood tests to assess your recovery and determine the best course of action.

In some cases, if the surgical margins are clear and there is no evidence of residual disease, the oncologist may decide to reduce the number of post-operative chemotherapy cycles. However, this decision will be based on a thorough evaluation of your specific situation and the latest clinical guidelines.

Moreover, it is essential to maintain regular follow-ups with your healthcare team to monitor your recovery and manage any side effects from the treatment. Ewing's sarcoma can be challenging, but advancements in treatment have significantly improved outcomes for many patients. The key is to adhere to the recommended treatment plan and stay proactive in your care.

In summary, after surgery for Ewing's sarcoma, you will likely need additional chemotherapy sessions, typically ranging from 2 to 4 cycles, depending on your specific case. Always consult with your oncologist to tailor the treatment plan to your needs and ensure the best possible outcome.

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