Chronic Cholecystitis: Symptoms, Risks, and Treatment Options - Gastroenterology and Hepatology

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Chronic cholecystitis


Chronic cholecystitis is a long-term inflammation of the gallbladder, often associated with the presence of gallstones.
Symptoms may include abdominal pain, particularly in the upper right quadrant, nausea, vomiting, and bloating, although some individuals may be asymptomatic.
The thickening of the gallbladder wall that you have experienced for the past two to three years may indicate ongoing inflammation, even in the absence of pain or other symptoms.
The presence of gallstones for five to six years without symptoms is not uncommon, and many individuals live with gallstones without requiring surgical intervention.
Whether or not to remove the gallbladder (cholecystectomy) depends on several factors, including the presence of symptoms, the size and number of gallstones, and the thickness of the gallbladder wall.
If you are asymptomatic and your condition is stable, continuing with annual ultrasound examinations may be sufficient.
However, it is essential to discuss your specific situation with your healthcare provider to determine the best course of action for your health.
Thank you.

Shen, 50~59 year old female. Ask Date: 2015/10/31

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, Sir: Local irritation from gallstones may lead to acute inflammation (acute pain).
It can also cause chronic inflammation (with less noticeable pain, but resulting in thickening of the gallbladder wall), which over time may lead to local cellular deterioration and the development of gallbladder cancer.
Therefore, it is generally recommended to remove the gallbladder; otherwise, annual monitoring is necessary as a precaution.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2015/10/31

More Info


Chronic cholecystitis is a long-standing inflammation of the gallbladder, often associated with the presence of gallstones. This condition can develop over time due to repeated episodes of acute cholecystitis or ongoing irritation from gallstones. The symptoms of chronic cholecystitis can be subtle and may include intermittent abdominal pain, particularly in the right upper quadrant, nausea, and digestive disturbances after meals, especially those high in fat. However, in some cases, patients may remain asymptomatic, as you have described.

The thickening of the gallbladder wall, which you mentioned, is a common finding in chronic cholecystitis. It indicates that there has been some degree of inflammation, even if you are not currently experiencing pain or other symptoms. The presence of gallstones can further complicate the situation, as they can lead to acute episodes of pain or inflammation if they obstruct the bile ducts or the gallbladder itself.

In terms of management, the decision to proceed with surgery, specifically cholecystectomy (gallbladder removal), often depends on several factors:
1. Symptomatology: If you are asymptomatic and have not experienced any episodes of pain or complications related to your gallstones, some physicians may recommend a conservative approach, which includes regular monitoring through ultrasound examinations. This is particularly true if the gallstones are small and not causing any obstruction.

2. Risk of Complications: Chronic cholecystitis can lead to complications such as acute cholecystitis, pancreatitis, or even gallbladder cancer, although the latter is rare. If there is a significant risk of these complications based on your medical history, the presence of gallstones, and the thickening of the gallbladder wall, surgical intervention may be advised.

3. Gallbladder Function: Sometimes, a HIDA scan (hepatobiliary iminodiacetic acid scan) can be performed to assess the function of the gallbladder. If the gallbladder is not functioning properly, this may also warrant surgical removal.

4. Patient Preference: Ultimately, the decision to undergo surgery should involve a discussion between you and your healthcare provider, taking into account your preferences, lifestyle, and any concerns you may have about the procedure.

Given that you have been asymptomatic for several years, it may be reasonable to continue with annual ultrasound monitoring, provided that your healthcare provider agrees. However, if you start experiencing symptoms such as pain, nausea, or any signs of complications, it would be prudent to revisit the discussion about surgical options.

In conclusion, while chronic cholecystitis and gallstones can often be managed conservatively, the potential for complications and changes in your condition should be closely monitored. Regular follow-ups with your healthcare provider are essential to ensure that you are making the best decision for your health. If you have any concerns or if your symptoms change, do not hesitate to seek medical advice.

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