Managing Side Effects of Urology Medications: Alternatives and Concerns - Urology

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Regarding the side effects of medications?


Hello, Doctor.
Thank you for your previous response.
After my last inquiry, I visited a family medicine clinic where I had a urine test, but I haven't received the report yet.
Based on my description, they suggested it might be a urethral abrasion and prescribed Refexin 500mg (brand: Ruian, white and green capsule), which is likely intended to prevent bacterial infection.
However, I forgot to mention that I have gastrointestinal issues, so I am experiencing the gastrointestinal side effects noted on the medication label.
Since I need to take it for five days, I would like to ask the doctor: 1.
Are there any alternative medications that are less harsh on the stomach? 2.
If I continue taking it for five days and then stop, will my gastrointestinal condition return to normal? I am concerned that I might end up with gastrointestinal discomfort after finishing the medication and need to seek further treatment.
3.
Regarding the urethral abrasion, the doctor mentioned kidney stones; are there any other potential causes for a urethral abrasion? Thank you, Doctor.

Mr. Wu, 20~29 year old female. Ask Date: 2015/11/06

Dr. Xu Weikai reply Urology


Hello Mr.
Wu, Refexin is a medication that is unlikely to cause gastrointestinal discomfort.
Very few patients require antacids.
If you are experiencing discomfort, we can either switch medications or add an antacid.
Any irritation from the medication can resolve after discontinuation.
Other irritants such as infections, injuries, or soaps may also contribute.
If you have any further questions, feel free to ask, and we can discuss this further.
Please remember that online responses should only be used as a reference; it is essential to seek medical attention at a healthcare facility if necessary.
The Ministry of Health and Welfare Taitung Hospital cares about you.

Reply Date: 2015/11/06

More Info


Managing side effects from urology medications can be a significant concern for patients, especially when dealing with chronic conditions such as chronic pelvic pain syndrome or urinary tract issues. In your case, it seems you are experiencing gastrointestinal discomfort due to the medication Refexin (a brand of rifaximin), which is commonly prescribed to prevent bacterial infections. Let's address your questions and concerns systematically.

1. Alternatives to Refexin: If you have a history of gastrointestinal issues, it is essential to communicate this with your healthcare provider. There are alternative antibiotics that may be less irritating to the stomach, such as azithromycin or certain cephalosporins, which might be better tolerated. Additionally, some healthcare providers may consider prescribing probiotics alongside antibiotics to help mitigate gastrointestinal side effects. Always consult your doctor before making any changes to your medication regimen.

2. Recovery of Gastrointestinal Health Post-Medication: Generally, if you continue taking Refexin for the prescribed five days, your gastrointestinal discomfort should resolve after completing the course, provided that you do not have an underlying condition that predisposes you to gastrointestinal issues. However, if you experience significant discomfort or symptoms such as severe nausea, vomiting, or diarrhea, it is crucial to contact your healthcare provider immediately. They may recommend supportive care, such as hydration and dietary adjustments, to help your gut recover.

3. Causes of Urethral Injury: Urethral injuries can occur due to various reasons beyond kidney stones. Other potential causes include trauma (such as from vigorous sexual activity or accidents), infections that lead to inflammation, or even certain medical procedures. In some cases, conditions like urethral strictures or benign prostatic hyperplasia (BPH) can contribute to urethral irritation or injury. It’s essential to have a thorough evaluation by a urologist to determine the exact cause of your symptoms and to tailor the treatment accordingly.

In managing the side effects of urology medications, it is also important to consider lifestyle modifications. Staying well-hydrated can help dilute urine and reduce irritation in the urinary tract. Additionally, avoiding irritants such as caffeine, alcohol, and spicy foods may help alleviate urinary symptoms.

If you continue to experience side effects or if your symptoms worsen, do not hesitate to reach out to your healthcare provider. They can provide further evaluation and may refer you to a specialist if necessary. Remember, effective communication with your healthcare team is key to managing your condition and any associated side effects effectively.

In conclusion, while medications like Refexin are essential for treating infections, their side effects can be challenging, especially for those with pre-existing gastrointestinal issues. Exploring alternatives, understanding the recovery process, and identifying the underlying causes of your symptoms are crucial steps in managing your health effectively. Always prioritize open communication with your healthcare provider to ensure the best possible outcomes for your treatment.

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