Elevated White Blood Cell Count and Cholesterol Levels - Family Medicine

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Elevated white blood cell count and elevated cholesterol levels?


Hello: Recently, my physical examination showed a white blood cell count of 10.76 x 10^3/µL and cholesterol level of 201.
I have no discomfort in my body.
I would like to know if long-term night shift work could be affecting these results.
How can I improve this? Thank you.

A Niu, 30~39 year old female. Ask Date: 2015/11/18

Dr. Chen Bozhang reply Family Medicine


Dear Mr.
A-Niu,
Your recent health check-up indicated elevated white blood cell counts and slightly high cholesterol levels.
White blood cells are one of the indicators of inflammation in the body, and their increase can be caused by various factors, including infections, rheumatic autoimmune diseases, or other inflammatory conditions.
Long-term night shift work can affect stress hormones, leading to chronic inflammation; however, this is not the only reason for elevated white blood cell counts.
Since you are not experiencing any discomfort, I recommend that you follow up with a family medicine or general internal medicine clinic in three months to recheck your levels and discuss potential causes with your physician.
Regarding cholesterol, the reference range for total cholesterol in adults is 130-200 mg/dL.
There are various types of cholesterol, but the most commonly used to assess cardiovascular disease risk are high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol.
HDL is considered "good" cholesterol, while LDL is referred to as "bad" cholesterol.
Since you did not provide the values for HDL and LDL cholesterol, I suggest that when you visit a family medicine or general internal medicine clinic, you request these tests to evaluate your cardiovascular disease risk alongside your total cholesterol.
Additionally, the best way to improve cholesterol levels is through regular aerobic exercise.
Engaging in at least 150 minutes of moderate-intensity aerobic exercise each week can enhance cholesterol metabolism and improve cardiovascular protection.
I hope this information is helpful to you.
Sincerely,
Dr.
Chen Po-Chang
Department of Family Medicine
Keelung Hospital, Ministry of Health and Welfare

Reply Date: 2015/11/18

More Info


Elevated white blood cell (WBC) counts and cholesterol levels can be concerning, but understanding their implications requires a comprehensive approach. Your reported WBC count of 10.76 x 10^3/µL is slightly elevated, as the normal range typically falls between 4.0 and 10.0 x 10^3/µL. Cholesterol levels, on the other hand, are generally considered normal if they are below 200 mg/dL, so a level of 201 mg/dL is marginally elevated.


Understanding Elevated WBC Count
An elevated WBC count, known as leukocytosis, can occur for various reasons. It is essential to consider the context in which the elevation occurs. Common causes include:
1. Infections: The body often responds to infections by increasing WBC production to fight off pathogens.

2. Inflammation: Conditions such as autoimmune diseases or inflammatory disorders can lead to elevated WBC counts.

3. Stress: Physical or emotional stress can temporarily increase WBC levels.

4. Allergic Reactions: Allergies can also cause an increase in specific types of white blood cells.

5. Bone Marrow Disorders: In rare cases, elevated WBC counts can indicate more serious conditions, such as leukemia or other bone marrow disorders.

Given that you mentioned you have no symptoms, it is possible that your elevated WBC count could be related to stress or lifestyle factors, including your work schedule. Working night shifts can disrupt your circadian rhythm, potentially leading to increased stress and fatigue, which may influence your immune response and WBC production.


Cholesterol Levels
Regarding your cholesterol level of 201 mg/dL, this is slightly above the recommended threshold. Elevated cholesterol can be influenced by several factors, including:
1. Diet: High intake of saturated fats, trans fats, and cholesterol can raise blood cholesterol levels.

2. Physical Activity: A sedentary lifestyle can contribute to higher cholesterol levels.

3. Weight: Being overweight or obese can negatively impact cholesterol levels.

4. Genetics: Family history can play a significant role in cholesterol levels.


Recommendations for Improvement
To address both elevated WBC and cholesterol levels, consider the following lifestyle modifications:
1. Dietary Changes: Adopt a heart-healthy diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats (such as those found in fish, nuts, and olive oil). Limit saturated fats and trans fats, which are commonly found in processed foods.

2. Regular Exercise: Aim for at least 150 minutes of moderate aerobic activity each week. Exercise can help lower cholesterol levels and improve overall health.

3. Stress Management: Since your work schedule may contribute to stress, consider incorporating stress-reducing activities into your routine, such as yoga, meditation, or deep-breathing exercises.

4. Regular Health Check-ups: Keep regular appointments with your healthcare provider to monitor your blood counts and cholesterol levels. They can provide personalized advice and may recommend further testing if necessary.

5. Sleep Hygiene: Prioritize good sleep practices, especially since night shifts can disrupt your sleep cycle. Aim for a consistent sleep schedule and create a restful environment.


Conclusion
While your elevated WBC count and cholesterol levels warrant attention, they can often be managed through lifestyle changes. It is essential to consult with your healthcare provider for a thorough evaluation and personalized recommendations based on your health history and lifestyle. Regular monitoring and proactive management can help you maintain optimal health and prevent potential complications.

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