High White Blood Cell Count and Lipid Levels: Key Health Insights

Elevated white blood cell count, triglycerides, total cholesterol, and fasting blood glucose levels?

Hello Doctor: I recently had blood tests done on March 6, which included urine, blood, liver, and kidney function tests.
The results showed elevated white blood cells (17,140), triglycerides (446), total cholesterol (211), and fasting blood glucose (126).
The white blood cell count is particularly concerning, and I have a history of high triglycerides (up to 600), for which I have been taking a well-known medication, Rosuvastatin (10 mg, approximately 15 tablets taken, with a maximum of 2 tablets daily, spaced 12 hours apart).
However, I experienced noticeable dizziness (not severe enough to affect daily life) and stopped taking Rosuvastatin for nearly two months before the blood test due to frequent gastrointestinal discomfort and bloating.
During the time I was on the medication, I lost about 8 kg (from 88 kg to 80 kg at 175 cm).
Additionally, I have been experiencing pain in my left upper arm and shoulder from a previous work injury, which sometimes requires injections for relief, and I also have chronic headaches for which I take acetaminophen.
I have a smoking habit (about a pack a day) but do not cough.
Most of my sleep occurs during the day, and I work at night, a routine I have maintained for about four years.
Given this recent situation, I would like to ask:
1.
Regarding the elevated white blood cell count, should I seek further testing immediately, or is it advisable to monitor the situation before proceeding?
2.
My triglycerides remain high at 446.
Due to gastrointestinal discomfort and dizziness, I have not continued taking the medication.
Are there alternative approaches I can consider, or should I wait until my symptoms improve before resuming the medication? (I suspect that my high triglycerides may be related to consuming large amounts of sugary drinks, like soda, during the summer, but I have significantly reduced my intake since starting the medication.)
3.
Is a fasting blood glucose level of 126 indicative of diabetes?
Note: All other test values were normal.
The tests included: Urine: urine, protein, occult blood, red blood cells, white blood cells, epithelial cells, casts, bacteria; Blood: red blood cells, hemoglobin, platelets; Kidney function: urea nitrogen, creatinine, uric acid; Liver function: SGOT, SGPT, albumin, globulin, A/G ratio, total protein.
Thank you.

A-Hsien, 50~59 year old female. Ask Date: 2017/03/09

Dr. Chen Taicheng reply Family Medicine

● There are many causes for elevated white blood cell counts, including inflammation, infection, or other diseases.
It is advisable to monitor for symptoms such as fever, sore throat, diarrhea, or other recent significant physical discomfort.
If none are present, it is still recommended to have a follow-up white blood cell count test in one to two weeks with an infectious disease or hematology specialist.

● Elevated triglycerides can be influenced by genetic factors, as well as excessive intake of carbohydrates, high-fat foods, obesity, alcohol consumption, smoking, certain medications (such as diuretics), or other medical conditions (such as diabetes, kidney issues, or hypothyroidism).
High triglyceride levels increase the risk of acute pancreatitis.

● The primary methods for lowering hyperlipidemia include dietary changes, exercise, weight loss, and lifestyle modifications, with medications serving as an adjunct.
Besides statins (currently the most potent medication), there are other medications with different mechanisms and potencies available; please discuss these options with your physician.
Taking a single statin after meals may help alleviate gastrointestinal discomfort and dizziness.

● In healthy individuals, fasting blood glucose levels should be ≤100 mg/dL.
Fasting blood glucose levels of 101-125 mg/dL indicate prediabetes, while levels ≥126 mg/dL indicate diabetes.
However, a single test cannot definitively diagnose diabetes; further testing is required.
If you are at risk for diabetes, in addition to dietary changes, exercise, weight loss, and lifestyle modifications, it is important to monitor carbohydrate intake and regularly check blood glucose, blood pressure, and lipid levels (the lipid targets for diabetics are stricter than for the general population, with LDL cholesterol needing to be <100 mg/dL).
Please consult a family medicine or endocrinology specialist for further evaluation.

● Quitting smoking can reduce the risk of the three highs (hypertension, hyperglycemia, and hyperlipidemia) and decrease inflammation in the body.
Many healthcare facilities offer outpatient smoking cessation services (our family medicine department also provides this service), with a success rate 5 to 6 times higher than attempting to quit on your own; feel free to inquire.
Individuals over 30 who smoke or chew betel nut should undergo oral mucosa examinations every two years at hospitals or health centers.
Please take advantage of this service.
Wishing you good health, Dr.
Chen Tai-Cheng from the Family Medicine Department at Taoyuan Hospital cares for you.

Reply Date: 2017/03/09

More Info

High white blood cell (WBC) count, elevated triglycerides, and increased fasting blood glucose levels can indicate several underlying health issues that warrant further investigation and management. Let's break down your concerns and provide insights based on your blood test results.

1. Understanding High White Blood Cell Count
A WBC count of 17,140 cells per microliter is significantly elevated, as the normal range is typically between 4,500 and 11,000 cells per microliter. High WBC counts can be indicative of various conditions, including:
- Infection or Inflammation: The body often increases WBC production in response to infections (bacterial, viral, or fungal) or inflammatory conditions.

- Stress Response: Physical or emotional stress can lead to a temporary increase in WBC count.

- Chronic Conditions: Conditions such as autoimmune diseases, allergies, or even certain cancers (like leukemia) can cause elevated WBC counts.

- Medication Effects: Some medications, including corticosteroids, can also elevate WBC counts.

Given your significantly elevated WBC count, it is advisable to consult a healthcare provider for further evaluation. They may recommend additional tests, such as a complete blood count with differential, to assess the types of white blood cells present and determine the cause of the elevation.

2. Elevated Triglycerides and Management
Your triglyceride level of 446 mg/dL is considered high (normal is below 150 mg/dL). Elevated triglycerides can increase the risk of cardiovascular disease and may be influenced by several factors, including diet, weight, physical activity, and genetics. Here are some strategies to manage high triglycerides:
- Dietary Changes: Reducing sugar intake, especially from sugary beverages, and limiting refined carbohydrates can help lower triglyceride levels. Incorporating more omega-3 fatty acids (found in fish like salmon and walnuts) and fiber-rich foods (like fruits, vegetables, and whole grains) can also be beneficial.

- Regular Exercise: Engaging in regular physical activity can help lower triglycerides and improve overall heart health.

- Weight Management: Since you mentioned a weight loss of 8 kg, continuing to maintain a healthy weight can positively impact triglyceride levels.

- Medication: If lifestyle changes are insufficient, your healthcare provider may consider resuming medication or adjusting your treatment plan. If you experienced side effects from your previous medication, discuss these with your doctor to find a suitable alternative.

3. Fasting Blood Glucose Levels
A fasting blood glucose level of 126 mg/dL is at the threshold for diagnosing diabetes. According to the American Diabetes Association, a fasting blood glucose level of 126 mg/dL or higher on two separate tests indicates diabetes. However, a single elevated reading does not confirm a diagnosis. It is essential to:
- Monitor Blood Glucose: Regular monitoring can help track your blood sugar levels and identify patterns.

- Lifestyle Modifications: Similar to managing triglycerides, adopting a balanced diet low in refined sugars and carbohydrates, increasing physical activity, and maintaining a healthy weight can help manage blood sugar levels.

- Consult a Healthcare Provider: It is crucial to discuss your fasting glucose levels with your healthcare provider. They may recommend further testing, such as an HbA1c test, to assess your average blood sugar levels over the past two to three months.

Conclusion
In summary, your elevated WBC count, triglycerides, and fasting blood glucose levels indicate potential health issues that require further evaluation and management. It is essential to consult with a healthcare provider to determine the underlying causes and develop a comprehensive treatment plan tailored to your needs. Lifestyle modifications, regular monitoring, and possibly medication adjustments will play a crucial role in managing your health effectively.

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Sorry! The information you provided is incomplete. Please attach the data from the test report. Thank you!