Mitral Valve Prolapse: Symptoms, Tests, and Long-Term Medication Effects - Cardiology

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Mitral valve prolapse


Hello Doctor, I am 23 years old.
I was diagnosed with mitral valve prolapse and arrhythmia during middle school and started medication for control.
In the past two years, I have been found to have regurgitation, and I have been experiencing increased frequency of dizziness, chest pain, hand tremors, and insomnia.
I would like to know what other tests are recommended besides echocardiography and 24-hour Holter monitoring.
Additionally, I am currently taking propranolol, AMPRAM TABLETS, and Longcardio, almost daily, and I tend to take more when I feel unwell.
I have been on these medications for nearly 10 years.
Will long-term medication control lead to dependence or harm? I appreciate your time in addressing these questions.
Thank you!

Nìngmíng, 20~29 year old female. Ask Date: 2015/11/20

Dr. He Dongjin reply Cardiology


Hello, your concern should be that the use of the aforementioned medication is appropriate for long-term management and should not cause dependence or harm.
There is no need to worry.
Changhua Hospital cares about you.

Reply Date: 2015/11/20

More Info


Mitral valve prolapse (MVP) is a condition where the mitral valve, located between the left atrium and left ventricle of the heart, does not close properly. This can lead to mitral regurgitation, where blood leaks backward into the atrium. Symptoms can vary widely; some individuals may experience no symptoms at all, while others may report palpitations, chest pain, dizziness, anxiety, or fatigue. In your case, the symptoms of dizziness, chest pain, tremors, and increased insomnia are concerning and warrant further evaluation.

In addition to echocardiography and a 24-hour Holter monitor, which you have already undergone, other tests that may be beneficial include:
1. Electrocardiogram (ECG): This can help identify any arrhythmias or abnormal heart rhythms that may be contributing to your symptoms.

2. Exercise Stress Test: This test can assess how your heart performs under physical stress and can help identify any exercise-induced arrhythmias.

3. Cardiac MRI: If there are concerns about the structure of your heart or the severity of the regurgitation, a cardiac MRI can provide detailed images of the heart's anatomy and function.

4. Blood Tests: Checking for thyroid function, electrolyte levels, and other markers can help rule out other causes of your symptoms.

Regarding your long-term medication regimen, it is important to understand the medications you are taking. Propranolol is a beta-blocker commonly used to manage symptoms associated with MVP, such as palpitations and anxiety. Long-term use of beta-blockers is generally considered safe, but it is essential to monitor for potential side effects, including fatigue, dizziness, and bradycardia (slow heart rate).
Amprazole (likely referring to a proton pump inhibitor) is often used to manage gastrointestinal symptoms, which can sometimes accompany MVP. Long-term use of proton pump inhibitors can lead to side effects such as nutrient malabsorption (e.g., magnesium, calcium, and vitamin B12), increased risk of gastrointestinal infections, and potential kidney issues.

Longcardio (likely referring to a medication for heart rhythm management) should be monitored closely, especially if you have been on it for an extended period. It is crucial to have regular follow-ups with your healthcare provider to assess the effectiveness of your treatment and to adjust dosages as needed.

Regarding your concern about dependency and harm from long-term medication use, it is essential to differentiate between physical dependence and the need for ongoing treatment. While some medications can lead to withdrawal symptoms if stopped abruptly, others, like beta-blockers, may require gradual tapering under medical supervision.
In your case, it is advisable to maintain open communication with your healthcare provider about your symptoms and any concerns regarding your medications. They can help determine if your current regimen is appropriate or if adjustments are necessary. Regular follow-ups and monitoring can help mitigate potential risks associated with long-term medication use.

In summary, MVP can lead to various symptoms, and while long-term medication can be necessary for management, it is crucial to have regular evaluations to ensure that the treatment remains effective and safe. If you experience any new or worsening symptoms, do not hesitate to seek medical attention.

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