Hello, doctor. Does excessive exercise lead to abnormalities in liver function tests such as CCF and GOT?
Hello, doctor.
Recently, I have been exercising a lot and eating very little.
Despite having some anemia, I thought my diet was healthy, but I noticed that my CCF is +1 and my GOT is 47 (normal range 8-38).
Could this be related to my daily one-hour jogging? Additionally, I have two other values close to the critical threshold: beta-lipoprotein at 496 (normal range 200-500) and total lipids at 599 (normal range 400-1000).
Are these related to my dieting or intense exercise? Thank you, doctor.
Cao Er, 10~19 year old female. Ask Date: 2015/11/23
Dr. Chen Shidian reply Gastroenterology and Hepatology
Hello, sir: These tests are mostly insignificant, so there is no need to worry too much.
GOT can be released into the bloodstream due to muscle activity, so you can rest for a few days and then retest.
Changhua Hospital cares about your health.
Chen Shidian
Reply Date: 2015/11/23
More Info
Intense exercise can indeed have an impact on liver function tests and overall blood health. When you engage in vigorous physical activity, your body undergoes various physiological changes that can affect the levels of certain enzymes and proteins in your blood, including those related to liver function.
One of the key enzymes that can be affected by exercise is GOT (Glutamate Oxaloacetate Transaminase), also known as AST (Aspartate Aminotransferase). Elevated levels of GOT can indicate liver damage or dysfunction; however, it is important to note that exercise can also lead to transient increases in this enzyme due to muscle breakdown. When you exercise, especially if it's intense or prolonged, muscle tissue can be damaged, leading to the release of GOT into the bloodstream. This is particularly relevant for individuals who may not be accustomed to high levels of physical activity or who are engaging in new or strenuous workouts.
In your case, the GOT level of 47 (normal range 8-38) could be attributed to your increased exercise routine. It is advisable to allow some time for recovery and then retest the levels to see if they normalize. Additionally, the CCF (Complete Blood Count) showing a positive result could indicate various factors, including dehydration or changes in blood volume due to exercise and dietary changes, especially if you have been eating less.
Regarding your lipid levels, the beta-lipoprotein and total lipid levels nearing the upper limits of normal could also be influenced by your dietary habits and exercise regimen. While regular exercise is generally beneficial for lipid profiles, significant dietary restrictions can lead to fluctuations in lipid metabolism. If your diet is low in calories or essential nutrients, your body may respond by altering how it processes fats, potentially leading to elevated lipid levels.
It is also essential to consider the potential for anemia, especially if you are experiencing fatigue or weakness. Intense exercise combined with inadequate nutrition can exacerbate anemia, which may further affect your overall health and recovery. Ensuring that you consume a balanced diet rich in iron, vitamins, and minerals is crucial for maintaining blood health, particularly if you are engaging in regular exercise.
In summary, while intense exercise can lead to temporary changes in liver function tests and blood health, it is essential to monitor these changes over time and consider other factors such as diet and overall health. If you continue to experience abnormal test results or symptoms, it would be prudent to consult with a healthcare professional for further evaluation and guidance. Regular follow-up tests, a balanced diet, and appropriate hydration can help manage these issues effectively.
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