Post-Gonorrhea Treatment Concerns: Symptoms and Recovery - Urology

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Post-treatment for gonorrhea?


Hello Dr.
Hsu, I visited a massage parlor on November 1st, and on November 7th, I noticed redness and swelling at the urethral opening, along with a prickling itch in the penile urethra and yellowish-white discharge.
On November 12th, a urologist diagnosed me with gonococcal urethritis.
I received one injection of Tricef 1000mg/1 vial (IV) on both November 12th and 13th, and I started taking Doxycycline 100mg, three capsules daily, from November 12th for two weeks until November 26th.
On November 26th, a urine test at the urology clinic showed no signs of inflammation.
The doctor performed a digital rectal exam to massage my prostate, allowing the prostatic fluid to be expelled, and mixed my urine with the prostatic fluid for a gonorrhea PCR test.
I continued taking Doxycycline 100mg, three capsules daily, from November 26th to December 3rd.
On December 3rd, the test results from the urine and prostatic fluid were negative.
That day, I also provided a semen sample for a gonorrhea PCR test.
From December 3rd to December 10th, I continued taking Doxycycline 100mg, two capsules daily.
On December 10th, the semen test results were negative, and the doctor said I was cured, as there were no gonococci in my urine, prostatic fluid, or semen, indicating that everything was okay.
The doctor mentioned that I did not need to return for follow-up.
However, since the treatment period until now, I occasionally still feel a slight prickling itch in the urethra, and the urethral opening appears somewhat red.
Could this indicate that the treatment was not fully effective? I am quite worried and kindly ask for your clarification.
Thank you!

Qiu, 30~39 year old female. Ask Date: 2015/12/22

Dr. Xu Weikai reply Urology


Hello, the physician mentioned that healing refers to the complete eradication of the bacteria.
However, the damage caused to the urethral epithelium by the previous infection will take some time to repair.
If there are any unclear points, feel free to ask again for further discussion and research.
Information obtained online should only be used as a reference; it is essential to seek medical care at a healthcare facility when necessary.
This message is from Dr.
Hsu Wei-Kai, Director of the Urology Department at Taitung Hospital, Ministry of Health and Welfare.

Reply Date: 2015/12/22

More Info


Hello! Thank you for reaching out with your concerns regarding your post-gonorrhea treatment and the lingering symptoms you are experiencing. It's understandable to feel anxious after such an infection and treatment, especially when symptoms persist.

From your description, it appears that you were diagnosed with gonococcal urethritis and received appropriate treatment with both intravenous ceftriaxone and doxycycline. The fact that your follow-up tests for gonorrhea came back negative is a positive sign, indicating that the infection has been effectively treated. However, the symptoms you are experiencing, such as a tingling sensation in the urethra and slight redness at the urethral opening, can be concerning.

There are several potential explanations for these lingering symptoms:
1. Post-Infectious Inflammation: After an infection like gonorrhea, it is not uncommon for the urethra to remain inflamed for a period of time, even after the infection has been cleared. This condition is often referred to as post-infectious urethritis. The inflammation can lead to discomfort, tingling, and redness, which may take time to resolve.

2. Non-Gonococcal Urethritis (NGU): Sometimes, other organisms, such as Chlamydia trachomatis or Mycoplasma genitalium, can cause urethritis. If these were not tested for or treated, they could be responsible for your symptoms. It may be worth discussing with your healthcare provider whether additional testing for these pathogens is warranted.

3. Irritation or Sensitivity: The urethra can become sensitive after an infection, especially if there was any irritation during the examination or treatment process. This sensitivity can lead to feelings of discomfort even after the infection has resolved.

4. Psychological Factors: Anxiety and stress can also manifest as physical symptoms. If you are feeling particularly anxious about your health, this could contribute to the sensations you are experiencing.

Given that your healthcare provider has indicated that you are clear of gonorrhea, it may be beneficial to monitor your symptoms for a little while longer. However, if the symptoms persist or worsen, I recommend returning to your healthcare provider for further evaluation. They may consider additional tests or treatments to address any underlying issues.

In the meantime, here are a few suggestions to help manage your symptoms:
- Hydration: Drink plenty of fluids to help flush out your urinary tract.

- Avoid Irritants: Stay away from potential irritants such as alcohol, caffeine, and spicy foods, which can exacerbate urinary symptoms.

- Warm Compresses: Applying a warm compress to the area may provide some relief from discomfort.

- Relaxation Techniques: Engaging in relaxation techniques such as deep breathing or meditation can help manage anxiety.

In conclusion, while it is reassuring that your tests have come back negative, it is important to communicate any ongoing symptoms to your healthcare provider. They can help determine the best course of action to ensure your complete recovery. Don't hesitate to seek further medical advice if you feel uncertain or worried about your health. Take care!

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