How Soon Can You Get Pregnant After Ectopic Pregnancy Treatment? - Obstetrics and Gynecology

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After receiving methotrexate (MTX) treatment for an ectopic pregnancy, it is generally recommended to wait at least 3 months before attempting to conceive again. This allows time for the medication to clear from the body and for the reproductive system to return


Dear Doctor: I have an ectopic pregnancy.
In early December, I experienced heavy bleeding and underwent surgery, but the tissue report showed no embryonic tissue (the early gestational sac was also not visible).
My hCG levels continued to rise.
On December 16, I started receiving methotrexate (MTX) injections at a dose of 0.5 mg.
On December 18, I received the same dose of 0.5 mg, but the effect was poor, and my hCG levels continued to rise.
Therefore, on December 20, the dose was changed to 0.6 mg.
My pregnancy levels began to decrease after that, with doses of 0.6 mg on December 22, 24, and 26.
Although my levels continued to decline, the decrease was not significant, so my doctor decided to stop the MTX treatment.

I would like to ask how long it will take for the embryo to shrink and for my menstrual cycle to return before I can try to conceive again? Will this previous pregnancy affect the health of a future fetus? My attending physician mentioned that I could try to conceive after my next period, but I found articles online suggesting a wait of three months.
What would be the best timeframe for trying to conceive again? I am not young and am eager to have a second child.
Thank you, Doctor!

tina, 30~39 year old female. Ask Date: 2016/01/08

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it is generally recommended to wait until the BHCG levels return to normal and menstruation resumes before considering the process to be fully resolved.
This ensures that there are no issues when trying to conceive.
Typically, a waiting period of 2 to 3 months is advisable.
Wishing you good health.

Reply Date: 2016/01/08

More Info


After experiencing an ectopic pregnancy, it is understandable to have concerns about when it is safe to try to conceive again and whether any potential complications could affect a future pregnancy. The timeline for trying to conceive after an ectopic pregnancy can vary based on individual circumstances, including the treatment received and the body's recovery process.

In your case, it appears that you underwent a combination of surgical intervention and methotrexate (MTX) treatment to manage the ectopic pregnancy. Methotrexate is a medication commonly used to treat ectopic pregnancies as it helps to stop the growth of the pregnancy tissue. After the treatment, it is crucial to ensure that the HCG (human chorionic gonadotropin) levels return to normal, indicating that the ectopic tissue has been resolved.
Typically, healthcare providers recommend waiting for at least one menstrual cycle after the HCG levels have returned to zero before attempting to conceive again. This waiting period allows your body to heal and ensures that your next pregnancy is more likely to be healthy. The rationale behind this recommendation is that it allows for a clearer understanding of your menstrual cycle and ensures that any residual effects of the ectopic pregnancy or the treatment have subsided.

While some sources may suggest waiting for three months, this is often a more conservative approach and may not be necessary for everyone. The key factor is that your healthcare provider feels confident that your body has adequately recovered. If your doctor has advised that you can try to conceive after your next menstrual period, it is likely that they believe you are in a suitable condition to do so.

Regarding the impact of a subsequent pregnancy on the fetus, if you have fully recovered from the ectopic pregnancy and your HCG levels have normalized, there should not be any inherent risks to the fetus from the previous ectopic pregnancy itself. However, it is essential to monitor your health closely during the next pregnancy, especially if there were complications in the past. Regular prenatal care will help ensure that any potential issues are addressed promptly.

In summary, while the general recommendation is to wait for at least one menstrual cycle after your HCG levels have returned to normal, it is crucial to follow the guidance of your healthcare provider, who understands your specific medical history and circumstances. If you feel uncertain or anxious about the timing or any potential risks, do not hesitate to discuss your concerns further with your doctor. They can provide personalized advice and reassurance based on your health and fertility goals.

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